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Russian Journal of General Chemistry

, Volume 88, Issue 3, pp 566–572 | Cite as

Synthesis and Antimicrobial Activity of (Z)-3-{[3-Oxobenzofuran-2(3H)-ylidene]methyl}-4H-chromen-4-one Derivatives

  • S. Pervaram
  • D. Ashok
  • C. V. R. Reddy
  • M. Sarasija
  • B. A. Rao
Article
  • 31 Downloads

Abstract

A series of (Z)-3-{[3-oxobenzofuran-2(3H)-ylidene]methyl}-4H-chromen-4-one derivatives have been synthesized from 2-hydroxyl acetophenones by the Vilesmeier–Haack reaction, Claisen–Schmidt reaction and mercury(II) acetate/cupric bromide. All the synthesized compounds were characterized by IR, 1H and 13C NMR, and mass spectral data and elemental analysis. The products were tested for their in vitro antimicrobial activity.

Keywords

aurones chromanones benzofurans Vilesmeier–Haack reaction Claisen–Schmidt reaction mercury(II) acetate–cupric bromide antimicrobial activity 

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • S. Pervaram
    • 1
  • D. Ashok
    • 2
  • C. V. R. Reddy
    • 1
  • M. Sarasija
    • 3
  • B. A. Rao
    • 2
  1. 1.Department of ChemistryJawaharlal Nehru Technological UniversityHyderabadIndia
  2. 2.Green and Medicinal Chemistry Laboratory, Department of ChemistryOsmania UniversityHyderabadIndia
  3. 3.Department of ChemistrySatavahana UniversityKarimnagarIndia

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