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Investigation of Chemical Properties and Antimicrobial Activity of Acetylene Glycidyl Ethers

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Abstract

Reactions of acetylene glycidyl ethers with butylamine and ethylene diamine lead to the oxirane ring opening according to the Krasusky rule with the formation of acetylene aminoalcohols. In reaction with thiourea the oxygen atom in the ring is replaced by sulfur leading to the corresponding thiiranes in a high yield. The synthesized compounds possess high antimicrobial activity.

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Authors and Affiliations

  1. Institute of Polymer Materials, Azerbaijan National Academy of Sciences, S. Vurgun st. 124, Sumgait, AZ5004, Azerbaijan

    M. M. Movsumzade, M. I. Shatirova, U. Sh. Dzhafarova & N. K. Niyazova

Authors
  1. M. M. Movsumzade
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  2. M. I. Shatirova
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  3. U. Sh. Dzhafarova
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  4. N. K. Niyazova
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Corresponding author

Correspondence to M. I. Shatirova.

Additional information

Original Russian Text © M.M. Movsumzade, M.I. Shatirova, U.Sh. Dzhafarova, N.K. Niyazova, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 3, pp. 360–364.

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Movsumzade, M.M., Shatirova, M.I., Dzhafarova, U.S. et al. Investigation of Chemical Properties and Antimicrobial Activity of Acetylene Glycidyl Ethers. Russ J Gen Chem 88, 389–392 (2018). https://doi.org/10.1134/S1070363218030027

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  • DOI: https://doi.org/10.1134/S1070363218030027

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