Russian Journal of General Chemistry

, Volume 87, Issue 12, pp 2995–2999 | Cite as

An Efficient Synthesis of (R or S)-4-Methyl-1-(1,4,5,8-tetramethoxynaphthalen-2-yl)pent-3-ene-1-thiol

  • Guang Huang
  • Hui-ran Zhao
  • Wen Zhou
  • Qing-qing Meng
  • Qi-jing Zhang
  • Jin-yun Dong
  • Bao-quan Zhu
  • Shao-shun Li
Letters to the Editor
  • 3 Downloads

Abstract

Based on thilation by the Lawesson’s reagent (LR), a concise and efficient synthesis of (R or S)-4-methyl-1-(1,4,5,8-tetramethoxynaphthalen-2-yl)pent-3-ene-1-thiol was developed with relatively high yield.

Keywords

chiral thiol thilation Lawesson’s reagent sulfur-containing 

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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  • Guang Huang
    • 1
    • 2
  • Hui-ran Zhao
    • 3
  • Wen Zhou
    • 1
  • Qing-qing Meng
    • 1
  • Qi-jing Zhang
    • 1
  • Jin-yun Dong
    • 1
  • Bao-quan Zhu
    • 2
  • Shao-shun Li
    • 1
  1. 1.School of PharmacyShanghai Jiao Tong UniversityShanghaiChina
  2. 2.Shanghai Institute of Pharmaceutical IndustryShanghaiChina
  3. 3.School of Pharmaceutical Sciences and ChemistryDali UniversityDaliChina

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