Russian Journal of General Chemistry

, Volume 87, Issue 12, pp 2970–2978 | Cite as

Synthesis, Characterization, and Biological Activity of Organotin(IV) Complexes with Schiff Bases

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Abstract

The synthesized Schiff base ligands H2L1, N,N'-bis(2-hydroxybenzylidene)1,2-diaminobenzene, and H2L2, N,N'-bis(2-hydroxybenzylidene)hydrazine, reacted with Alk2SnCl2 to give organotin(IV) complexes 1–10. The products were characterized by elemental analysis, FTIR, 1H and 13C NMR, and mass spectrometry. All organotin(IV) derivatives with [O,N,O] donor ligands retained their 5-coordinated geometry in solid state and solutions. Most of synthesized complexes exhibited significant antibacterial activity. Cytotoxicity was also tested by using the brine shrimp (Artemia salina) lethality bioassay.

Keywords

Schiff base organotin(IV) IR NMR MS biological activity 

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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  1. 1.Department of ChemistryIMCG (PG), F-7/2IslamabadPakistan
  2. 2.Department of ChemistryQuaid-i-Azam UniversityIslamabadPakistan
  3. 3.Department of ChemistryUniversity of Sargodha, Lyallpur CampusFaisalabadPakistan
  4. 4.Department of ChemistryKohat University of Science and TechnologyKohat, KPKPakistan

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