Russian Journal of General Chemistry

, Volume 87, Issue 12, pp 2966–2969 | Cite as

Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-2-alkyloxy-6-substituted pyridine-3-carbonitriles

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Abstract

A group of new 2-alkyloxypyridine-3-carbonitriles linked pyrenyl-pyrazole functions has been obtained via reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different methyl aryl ketones. The newly compounds were assured by spectroscopic and elemental analysis.

Keywords

1,3,4-trisubstituted pyrazole derivatives pyridine-3-carbonitriles synthesis 

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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  1. 1.Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of PharmacyKing Saud UniversityRiyadhSaudi Arabia
  2. 2.Therapeutical Chemistry Department, Pharmaceutical and Drug Industries DivisionNational Research CentreDokki, CairoEgypt
  3. 3.Department of Chemistry, Faculty of ScienceMenoufia UniversityMenoufiaEgypt

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