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Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-6-(substituted phenyl)-1,2-dihydro-2-oxo(imino)pyridine-3-carbonitriles

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Abstract

A novel compounds of 4,6-diaryl-2-oxo(imino)-1,2-dihydro-pyridine-3-carbonitriles has been synthesized by reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different 1-(substituted phenyl)ethanones and ethyl cyanoacetate or malononitrile in presence of ammonium acetate. Structure of the newly synthesized compounds was elucidated from chemical and spectroscopic data.

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Authors and Affiliations

  1. Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia

    N. M. Khalifa & M. A. Al-Omar

  2. Therapeutical Chemistry Department, Pharmaceutical and Drug Industries Division, National Research Centre, Dokki, Cairo, 12622, Egypt

    N. M. Khalifa

  3. Department of Chemistry, Faculty of Medical and Applied Science, Taif University, Taif, Saudi Arabia

    O. M. Ali

Authors
  1. N. M. Khalifa
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  2. M. A. Al-Omar
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  3. O. M. Ali
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Corresponding author

Correspondence to N. M. Khalifa.

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The text was submitted by the authors in English.

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Khalifa, N.M., Al-Omar, M.A. & Ali, O.M. Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-6-(substituted phenyl)-1,2-dihydro-2-oxo(imino)pyridine-3-carbonitriles. Russ J Gen Chem 87, 2933–2936 (2017). https://doi.org/10.1134/S1070363217120349

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  • DOI: https://doi.org/10.1134/S1070363217120349

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