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Russian Journal of General Chemistry

, Volume 87, Issue 12, pp 2933–2936 | Cite as

Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-6-(substituted phenyl)-1,2-dihydro-2-oxo(imino)pyridine-3-carbonitriles

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Abstract

A novel compounds of 4,6-diaryl-2-oxo(imino)-1,2-dihydro-pyridine-3-carbonitriles has been synthesized by reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different 1-(substituted phenyl)ethanones and ethyl cyanoacetate or malononitrile in presence of ammonium acetate. Structure of the newly synthesized compounds was elucidated from chemical and spectroscopic data.

Keywords

1,3,4-trisubstituted pyrazoles 2-oxo(imino)pyridine derivatives synthesis 

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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  1. 1.Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of PharmacyKing Saud UniversityRiyadhSaudi Arabia
  2. 2.Therapeutical Chemistry Department, Pharmaceutical and Drug Industries DivisionNational Research CentreDokki, CairoEgypt
  3. 3.Department of Chemistry, Faculty of Medical and Applied ScienceTaif UniversityTaifSaudi Arabia

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