Cyclic Amidoalkylation of Hydrophosphorylic Compounds. Synthesis of Proline Analogs
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A method for the synthesis of N-Cbz-protected phosphorylic analogs of proline by cyclic amidoalkylation of various hydrophosphorylic compounds was developed. Combination of amide and carbonyl fragments in the 4-N-Cbz-aminobutyraldehyde molecule allows to realize the three-center two-component amide version of the Kabachnik–Fields reaction.
Keywordsphosphorylic analogs of proline cyclic amidoalkylation 4-aminobutyraldehyde
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