Abstract
The reaction in a mixture of 1,3-cyclohexanedione (dimedone), arylaldehyde, and ammonium acetate at 160°C during 10–15 min in the absence of solvent leads to the formation of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-diones. The structure of the products has been confirmed by IR and 1H NMR spectroscopy data. Antimicrobial activity of the obtained compounds has been studied.
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Original Russian Text © O.E. Nasakin, M.I. Kazantseva, V.L. Gein, 2017, published in Zhurnal Obshchei Khimii, 2017, Vol. 87, No. 1, pp. 160–161
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Nasakin, O.E., Kazantseva, M.I. & Gein, V.L. Synthesis of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2Н,5Н)-diones. Russ J Gen Chem 87, 154–155 (2017). https://doi.org/10.1134/S107036321701025X
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DOI: https://doi.org/10.1134/S107036321701025X