Russian Journal of General Chemistry

, Volume 87, Issue 1, pp 154–155 | Cite as

Synthesis of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2Н,5Н)-diones

Letters to the Editor


The reaction in a mixture of 1,3-cyclohexanedione (dimedone), arylaldehyde, and ammonium acetate at 160°C during 10–15 min in the absence of solvent leads to the formation of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-diones. The structure of the products has been confirmed by IR and 1H NMR spectroscopy data. Antimicrobial activity of the obtained compounds has been studied.


9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2Н,5Н)-dione Hantzsch synthesis antimicrobial activity 


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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  • O. E. Nasakin
    • 1
  • M. I. Kazantseva
    • 1
  • V. L. Gein
    • 2
  1. 1.Chuvash State UniversityCheboksaryRussia
  2. 2.Perm State Pharmaceutical AcademyPermRussia

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