Skip to main content
Log in

Prevention of Ischemic Stroke in Patients with an Atherosclerotic Lesion of the Carotid Arteries

  • From the Researcher’s Notebook
  • Published:
Herald of the Russian Academy of Sciences Aims and scope Submit manuscript

Abstract

Atherosclerotic lesions of the brachiocephalic arteries are one of the main causes of death and disability in the world population. The diagnosis of patients with atherosclerotic lesions of the carotid arteries and their division into symptomatic/asymptomatic are described in detail, and recommendations are given for the prevention of such lesions and on the treatment of such patients. The data of national studies forming the optimal indications for the use of one method or another of preventing acute cerebrovascular accidents with stenosis of the internal carotid artery are presented.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. A. S. Kadykov and N. V. Shakhparonova, “Early rehabilitation of stroke patients: The role of drug therapy,” Nervnye Bolezni, No. 1, 22–25 (2014).

    Google Scholar 

  2. E. J. Benjamin, M. J. Blaha, S. E. Chiuve, et al., “Heart disease and stroke statistics—2017 update: A report from the American Heart Association,” Circulation 135 (10), e146–e603 (2017).

    Article  Google Scholar 

  3. A. V. Gavrilenko, A. V. Kuklin, A. A. Kravchenko, and  V. V. Fomina, “Prediction and risk factors of perioperative neurological complications in patients with internal carotid artery stenosis,” Khirurgiya. Zh. im. N.I. Pirogova, No. 10, 109–112 (2017).

    Article  Google Scholar 

  4. J. M. Wardlaw, F. M. Chappell, M. Stevenson, et al., “Accurate, practical and cost-effective assessment of carotid stenosis in the UK,” Health Technol. Assess. 10 (30), 1–6 (2006).

    Article  Google Scholar 

  5. L. G. Stead, M. F. Bellolio, S. Suravaram, et al., “Evaluation of transient ischemic attack in an emergency department observation unit,” Neurocrit. Care 10 (2), 204–208 (2009).

    Article  Google Scholar 

  6. H. J. Barnett, D. W. Taylor, M. Eliasziw, et al., “North American Symptomatic Carotid Endarterectomy Trial Collaborators Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis,” N. Engl. J. Med. 339 (20), 1415–1425 (1998).

    Article  CAS  Google Scholar 

  7. P. J. Nederkoorn, Y. van der Graaf, and M. G. Hunink, “Duplex ultrasound and magnetic resonance angiography compared with digital subtraction angiography in carotid artery stenosis: A systematic review,” Stroke 34 (5), 1324–1332 (2003).

    Article  Google Scholar 

  8. E. S. Bartlett, T. D. Walters, S. P. Symons, and A. J. Fox, “Quantification of carotid stenosis on CT angiography,” Am. J. Neuroradiol. 27 (1), 13–19 (2006).

    CAS  Google Scholar 

  9. A. Gupta, G. Gialdini, M. P. Lerario, et al., “Magnetic resonance angiography detection of abnormal carotid artery plaque in patients with cryptogenic stroke,” J. Am. Heart Assoc. 4 (6), e002012 (2015).

    Google Scholar 

  10. N. Anzalone, F. Scomazzoni, R. Castellano, et al., “Carotid artery stenosis: Intraindividual correlations of 3D time-of-flight MR angiography, contrast-enhanced MR angiography, conventional DSA, and rotational angiography for detection and grading,” Radiology 236 (1), 204–213 (2005).

    Article  Google Scholar 

  11. H. J. Barnett, R. W. Gunton, M. Eliasziw, et al., “Causes and severity of ischemic stroke in patients with internal carotid artery stenosis,” J. Am. Med. Assoc. 283 (11), 1429–1436 (2000).

    Article  CAS  Google Scholar 

  12. Antiplatelet Trialists’ Collab., “Collaborative overview of randomized trial of antiplatelet therapy: 1. Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients,” BMJ 308 (6943), 1540 (1994).

    Article  Google Scholar 

  13. H. H. Eastcott, G. W. Pickering, and C. G. Rob, “Reconstruction of internal carotid artery in a patient with intermittent attacks of hemiplegia,” Lancet 264 (6846), 994– 996 (1954).

    Article  Google Scholar 

  14. A. V. Pokrovskii and V. N. Gontarenko, The State of Vascular Surgery in Russia in 2013 (Ross. Obshch. Angiol. i Sosud. Khirurg., Moscow, 2014) [in Russian].

    Google Scholar 

  15. A. R. Naylor, J. B. Ricco, G. J. de Borst, et al., “Management of atherosclerotic carotid and vertebral artery disease: 2017 clinical practice guidelines of the European society for vascular surgery (ESVS),” Eur. J. Vasc. Endovasc. Surg. 55 (1), 3–81 (2018).

    Article  Google Scholar 

  16. A. R. Naylor, “Time to rethink management strategies in asymptomatic carotid artery disease,” Nat. Rev. Cardiol. 9 (2), 116–124 (2011).

    Article  Google Scholar 

  17. “Endarterectomy for asymptomatic carotid artery stenosis: Executive committee for the asymptomatic carotid atherosclerosis study,” J. Am. Med. Assoc. 273 (18), 1421–1428 (1995).

  18. V. Aboyans, J. B. Ricco, M. E. L. Bartelink, et al., “ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European society for vascular surgery (ESVS),” Eur. J. Vasc. Endovasc. Surg. 55 (3), 305–368 (2018).

    Article  Google Scholar 

  19. J. F. Meschia, C. Bushnell, B. Boden-Albala, et al., “Guidelines for the primary prevention of stroke: A statement for healthcare professionals from the American Heart Association/American Stroke Association,” Stroke 45 (18), 3754–3832 (2014).

    Article  Google Scholar 

  20. P. P. Goodney, L. L. Travis, D. Malenka, et al., “Regional variation in carotid artery stenting and endarterectomy in the Medicare population,” Circ. Cardiovasc. Qual. Outcomes 3 (1), 15–24 (2010).

    Article  Google Scholar 

  21. K. Lokuge, D. D. de Waard, A. Halliday, et al., “Meta‑analysis of the procedural risks of carotid endarterectomy and carotid artery stenting over time,” Br. J. Surg. 105 (1), 26–36 (2018).

    Article  CAS  Google Scholar 

  22. W. Brooks, R. McClure, M. Jones, et al., “Carotid angioplasty and stenting versus carotid endarterectomy for treatment of asymptomatic carotid stenosis: A randomized trial in a community hospital,” Neurosurgery 54 (2), 318–324 (2004).

    Article  Google Scholar 

  23. T. Brott, R. Hobson, G. Howard et al., “Stenting versus endarterectomy for treatment of carotid-artery stenosis,” N. Engl. J. Med. 363 (1), 11–23 (2010).

    Article  CAS  Google Scholar 

  24. H. Eckstein, P. Ringleb, J. Allenberg, et al., “Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: A multinational, prospective, randomised trial,” Lancet Neurol. 7 (10), 893–902 (2008).

    Article  Google Scholar 

  25. J. Ederle, R. Featherstone, and M. Brown, “Randomized controlled trials comparing endarterectomy and endovascular treatment for carotid artery stenosis: A Cochrane systematic review,” Stroke 40 (4), 1373–1380 (2009).

    Article  Google Scholar 

  26. A. Hoffmann, S. Engelter, C. Taschner, et al., “Carotid artery stenting versus carotid endarterectomy—a prospective randomised controlled single-centre trial with long-term follow-up (BACASS),” Schweiz Arch. Neurol. Psychiatr. 159, 84–89 (2008).

    Article  Google Scholar 

  27. A. R. Naylor and J. B. Ricco, “European Society of Vascular Surgery guidelines on the management of atherosclerotic carotid and vertebral artery disease,” Eur. J. Vasc. Endovasc. Surg. 55 (6), 902 (2018).

    Article  Google Scholar 

  28. National Guidelines for the Management of Patients with Diseases of the Brachiocephalic Arteries (Angiologiya i Sosudistaya Khirurgiya, Moscow, 2013) [in Russian].

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to A. V. Gavrilenko, A. V. Kuklin, N. N. Al’-Yusef, G. F. Magomedova or S. O. Popov.

Additional information

Translated by B. Alekseev

RAS Academician Aleksandr Vasil’evich Gavrilenko is Head of the Cardiovascular Surgery Department of the Petrovskii National Research Center of Surgery (NRCS). Andrei Vadimovich Kuklin, Cand. Sci. (Med.), is a Leading Research Fellow of the NRCS Cardiovascular Surgery Department. Nadim Nasr Al’-Yusef is a Medical Doctor and Cardiovascular Surgeon at the same department. Gyurikhan Fazludinovna Magomedova is a Postgraduate Student of the above institute. Sergei Olego-vich Popov, Cand. Sci. (Med.), is Deputy Chief Physician for the Surgical Department, Petrovskii National Research Center of Surgery.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gavrilenko, A.V., Kuklin, A.V., Al’-Yusef, N.N. et al. Prevention of Ischemic Stroke in Patients with an Atherosclerotic Lesion of the Carotid Arteries. Her. Russ. Acad. Sci. 90, 751–754 (2020). https://doi.org/10.1134/S1019331620050135

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1019331620050135

Keywords:

Navigation