Algorithm for Calculating the Dissociation Constants of Ampholytes in Nonbuffer Systems
An algorithm for calculating the dissociation constants of ampholytes in aqueous solutions is developed on the basis of spectrophotometric data in the UV and visible ranges without pH measurements of a medium and without buffer solutions. The proposed algorithm has been experimentally tested for five ampholytes of different strengths. The relative error of measuring dissociation constants is less than 5%.
Keywordsthermodynamic dissociation constant spectrophotometric method UV–visible range aqueous solutions
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