Formation of Chiral Structures in UV-Initiated Formose Reaction
It has been found that the UV-initiated formose reaction in an extremely concentrated aqueous solution of formaldehyde gives sugars and other biologically significant chiral compounds with sp3-hybridized carbon atom. The reaction leads to an optically active condensed phase, which is a result of the spontaneous spatial separation of enantiomers in the racemate into the antipodes, similarly to the separation of enantiomers of different chirality sign in the famous Pasteur experiments. In our opinion, such a scenario is as close as possible to the actually realized de novo scenario of synthesis of chiral prebiotic molecules and matrices.
Unable to display preview. Download preview PDF.
- 2.Safronov, V. S., Evolyutsiya doplanetnogo oblaka i obrazovanie Zemli i planet (Evolution of the Preplanet Cloud and Formation of the Earth and Planets), Moscow, 1969.Google Scholar
- 3.Butlerov, A.M., K istorii proizvodnykh metilena, Sochineniya (To the History of Methylene Derivatives, Works), Moscow: Izd. Akademii Nauk SSSR, 1953, vol. 1, pp. 63–67.Google Scholar
- 15.Obolenskaya, A.V., El’nitskaya, Z.P., Leonovich, A.A., Laboratornye raboty po khimii drevesiny i tsellyulozy (Laboratory Manuals in the Chemistry of Wood and Cellulose), Moscow: Ekologiya, 1991.Google Scholar