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Biology Bulletin Reviews

, Volume 8, Issue 6, pp 509–517 | Cite as

Wolbachia Bacteria and Filarial Nematodes: Mutual Benefit and the Parasite’s Achilles’ Heel

  • E. V. ShaikevichEmail author
  • L. A. GanushkinaEmail author
Article
  • 27 Downloads

Abstract

The current information on symbiotic interrelations of the intracellular bacterium Wolbachia and filariae (parasites of human and animals), as well as evidence of the joint evolution of the symbiont and hosts, are discussed. Data on the absence of the joint distribution of this bacterium with its host in some Wolbachia supergroups are also presented. The results of morphological, genome, and transcriptomiс analyses obtained in the last ten years are provided. Insight into the biology and evolution of Wolbachia endosymbionts in the filarial organism, which were obtained by cytological, biochemical, and molecular methods, makes it possible to use the bacterium, which is obligate for filariae, in the treatment of human diseases.

Keywords:

symbiosis filariae Wolbachia pipientis 

Notes

ACKNOWLEDGMENTS

This work was supported by the Russian Foundation for Basic Research, project no. 16-04-00091.

COMPLIANCE WITH ETHICAL STANDARDS

Сonflict of interests. The authors declare that they have no conflict of interest.

Statement on the welfare of animals. This article does not contain any studies involving animals performed by any of the authors.

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  1. 1.Vavilov Institute of General Genetics, Russian Academy of SciencesMoscowRussia
  2. 2.Sechenov First Moscow State Меdical University Health of the Russian FederationMoscowRussia

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