Inland Water Biology

, Volume 11, Issue 4, pp 507–514 | Cite as

Features of the Immunophysiological Status of the Senegal Polypterus (Polypterus senegalus Cuvier, 1829)

  • T. B. LapirovaEmail author
  • E. A. Flerova


A comprehensive study of the main morphophysiological parameters of blood and immunocompetent organs of Polypterus senegalus Cuvier, 1829, one of the most ancient living species of fish, is presented. No fundamental differences in morphological or basic physiological and biochemical parameters of blood or the immune system in comparison with other fish species from polypterus are revealed. The investigated species has well-developed mechanisms of nonspecific protection and a high adaptive potential.


Polypterus senegalus blood immunocompetent organs physiological indices nonspecific immunity 



We are sincerely grateful to V.V. Yurchenko and A.A. Morozov for aid in obtaining the material. This study was supported by the Russian Foundation for Basic Research, grant no. 11-04-01168.


  1. 1.
    Anisimova, I.M. and Lavrovskii, V.V., Ikhtiologiya (Ichthyology), Moscow: Vysshaya Shkola, 1983.Google Scholar
  2. 2.
    Bakaneva, Yu.M., Bychkova, A.P., Bakanev, N.M., and Fedorovykh, Yu.V., Natural zeolites in production mixed fodders for Acipenseridae, Vestn. Altai. Gos. Tekh. Univ., Ser. Ryb. Khoz., 2009, nos. 1–2, pp. 59–60.Google Scholar
  3. 3.
    Balabanova, L.V., Ultrastructure of immunocompetent cells of some acipenserid species, Rybovod. Ryb. Khoz., 2009, no. 1-2, pp. 59–60.Google Scholar
  4. 4.
    Barannikova, I.A., Bayunova, L.V., Semenkova, T.B., and Trenkler, I.V., Changes in the physiological state of the hiemal form of the Russian sturgeon Acipenser gueldenstaedtii in the Volga after holding and hormonal impacts, J. Ichthyol., 2008, vol. 48, no. 5, pp. 402–407.CrossRefGoogle Scholar
  5. 5.
    Berestovskii, E.G. and Erokhina, I.A., Physiological and biochemical features of pikes of tundra and forest–tundra lakes of the Kola Peninsula, in Materialy XXVIII Mezhdunarodnoi konferentsii “Biologicheskie resursy Belogo morya i vnutrennikh vodoemov Evropeiskogo Severa” (Proc. XXVIII Int. Conf. “Biological Resources of the White Sea and Inland Water Bodies of European North”), Petrozavodsk, 2009, pp. 84–90.Google Scholar
  6. 6.
    Biktasheva, F.Kh., Biochemical blood indices of fishes in Lake Asylykul (Russia, Republic of Bashkortostan), Mezhdunar. Zh. Prikl. Fundam. Issled., 2010, no. 9, pp. 107–108.Google Scholar
  7. 7.
    Bichareva, O.N. and Musaev, M.A., Characteristics of hematological parameters and microelement composition of some organs of pond fishes, Vestn. Altai. Gos. Tekh. Univ., Ser. Ryb. Khoz., 2008, no. 3, pp. 71–74.Google Scholar
  8. 8.
    Vinogradov, G.D., Physiological and biochemical status of the commercial fish fauna under conditions of dissemination of xenobiotics in the Belaya River basin, Extended Abstract of Cand. Sci. (Biol.) Dissertation, Moscow, 2011.Google Scholar
  9. 9.
    Grinevich, Yu.A. and Alferov, A.N., Determination of immune complexes in the blood of cancer patients, Lab. Delo, 1981, no. 8, pp. 493–496.Google Scholar
  10. 10.
    Zhiteneva, L.D., Rudnitskaya, O.A., and Kalyuzhnaya, T.I., Ekologo-gematologicheskie kharakteristiki nekotorykh vidov ryb (Ecological and Hematological Characteristics of Some Fish Species), Rostov-on-Don: Molot, 1997.Google Scholar
  11. 11.
    Zakharova, L.A., Evolution of adaptive immunity, Biol. Bull. (Moscow), 2009, vol. 36, no. 2, pp. 107–116.CrossRefGoogle Scholar
  12. 12.
    Ivanova, N.T., Atlas kletok krovi ryb (Atlas of Fish Blood Cells), Moscow: Legkaya i Pishchevaya Prom-st', 1983.Google Scholar
  13. 13.
    Kozinenko, I.I., Isaeva, N.M., and Balakhnin, I.A., Humoral factors of nonspecific defense in fish, J. Ichthyol., 1999, vol. 39, no. 4, pp. 322–328.Google Scholar
  14. 14.
    Kokoza, A.A., Markov, E.E., and Noyaksheva, T.A., Some morphological and physiological indicators of juvenile acipenserids caught in the northern Caspian Sea and grown under artificial conditions, in Materialy IV Mezhdunarodnoi nauchno-prakticheskoi konferentsii “Akvakul’tura osetrovykh ryb: dostizheniya i perspektivy razvitiya, Astrakhan’ “ (Proc. IV Int. Sci.-Pract. Conf. “Aquaculture of Acipenseridae: Achievements and Prospects”), Moscow, 2006, pp. 85–88.Google Scholar
  15. 15.
    Kurovskaya, L.Ya., Lysenko, V.N., and Neborachek, S.I., Morphological and physiological indicators of some species of acipenserids (Acipenseridae, Acipenseriformes) of different age grown in aquaculture, Ribogospodar. Nauka Ukr., 2015, no. 1, pp. 108–119.Google Scholar
  16. 16.
    Lapirova, T.B., The effect of sublethal concentrations of mercury, copper, and cadmium on the immunophysiological status of juvenile Lena sturgeons, Biol. Vnutr. Vod, 2001, no. 3, pp. 80–84.Google Scholar
  17. 17.
    Lapirova, T.B., Some features of the formation of immune complexes in fishes, in Sbornik nauchykh trudov, posvyashchennykh 30-letiyu fakul’teta biologii i ekologii Yaroslavskogo Gosudarstvennogo Universiteta (Collection of Scientific Papers Dedicated to the 30th Anniversary of the Faculty of Biology and Ecology of Yaroslavl State University), Yaroslavl: Yarosl. Gos. Univ., 2001, pp. 242–245.Google Scholar
  18. 18.
    Lapirova, T.B. and Flerova, E.A., Comparative analysis of some immunophysiological blood parameters of pike Esox lucius (L.) and walleye Stizostedion lucioperca (L.), Vestn. Astrakh. Gos. Tekh. Univ., Ser. Ryb. Khoz., 2013, no. 1, pp. 140–146.Google Scholar
  19. 19.
    Lapirova, T.B., Flerova, E.A., Yurchenko, V.V., and Morozov, A.A., Protective systems of immunocompetent organs in fishes from different ecological and systematic groups, J. Ichthyol., 2017, vol. 57, no. 3, pp. 458–466.CrossRefGoogle Scholar
  20. 20.
    Loginov, S.I., Smirnov, P.N., and Trunov, A.N., Immunnye kompleksy u zhivotnykh i cheloveka: norma i patologiya (Immune Complexes in Animals and Humans: Health and Disease), Novosibirsk: Ross. Akad. S-kh. Nauk, Sib. Otd., Inst. Eksp. Vet. Sib. Dal’nego Vostoka, 1999.Google Scholar
  21. 21.
    Luk'yanenko, V.I., Immunobiologiya ryb: vrozhdennyi immunitet (Fish Immunobiology: Innate Immunity), Moscow: Agropromizdat, 1989.Google Scholar
  22. 22.
    Lutsenko, V.K., Molekulyarnaya patofiziologiya (Molecular Pathophysiology), Moscow: MAIK Nauka/Interperiodika, 2004.Google Scholar
  23. 23.
    Makashev, E.K., Kim, T.D., Smagulova, Z.Sh., and Makarushko, S.G., Changes in blood biochemical parameters of acipenserids fed with different types of feed, Vestn. Nats. Akad. Nauk Resp. Kaz., 2011, no. 5, pp. 28–30.Google Scholar
  24. 24.
    Mayanskii, D.N., Problems of immunity in general pathology, in Metodicheskie aspekty sovremennoi immunologii: Sb. nauch. tr. (Methodological Aspects of Modern Immunology: Collected Scientific Papers), Novosibirsk: Nauka, 1991, pp. 74–84.Google Scholar
  25. 25.
    Nelson J.S. Fishes of the world. N.Y.: John Wiley & Sons, Inc., 2006.Google Scholar
  26. 26.
    Plisetskaya, E.M., Gormonal’naya regulyatsiya uglevodnogo obmena u nizshikh pozvonochnykh (Hormonal Regulation of Carbohydrate Metabolism in Lower Vertebrates), Leningrad: Nauka, 1975.Google Scholar
  27. 27.
    Praktikum po immunologii: Uch. posobie (A Practical Course in Immunology: A Manual), Moscow: Mosk. Gos. Univ., 2002.Google Scholar
  28. 28.
    Romer, A.S. and Parsons, T.S., The Vertebrate Body, New York: CBS College Publ., 1986.Google Scholar
  29. 29.
    Flerova, E.A., Kletochnaya organizatsiya pochek kostistykh ryb (na primere otryadov Cypriniformes i Perciformes) (Cellular Organization of Kidneys of Teleosts (As Exemplified by Orders Cypriniformes and Perciformes)), Yaroslavl: Yarosl. Gos. S-kh. Akad., 2012.Google Scholar
  30. 30.
    Agius, C., Melano-macrophage centers and their role in fish pathology, J. Fish Dis., 2003, vol. 26, no. 9, pp. 499–509.CrossRefGoogle Scholar
  31. 31.
    Dalmo, R.A., Ingerbrigtsen, K., and Bogwald, J., Non-specific defense mechanism in fish with special reference to the reticuloendothelial system (RES), J. Fish Dis., 1997, vol. 20, pp. 241–273.CrossRefGoogle Scholar
  32. 32.
    Feng, G., Shi, X., Huang, X., and Zhuang, P., Oxidative stress and antioxidant defenses after long-term fasting in blood of Chinese sturgeon (Acipenser sinensis), Proсedia Environ. Sci., 2011, vol. 8, pp. 469–475.CrossRefGoogle Scholar
  33. 33.
    Grinde, B., Jolles, J., and Jolles, P., Purification and characterization of two lysozymes from rainbow trout (Salmo gairdneri), Eur. J. Biochem., 1988, vol. 173, pp. 269–73.CrossRefGoogle Scholar
  34. 34.
    Lie, O., Evensen, O., Sorensen, A., and Froysadal, E., Study on lysozyme activity in some fish species, Dis. Aquat. Org., 1989, vol. 6, pp. 1–5.CrossRefGoogle Scholar
  35. 35.
    Magnadottir, B., Innate immunity of fish (overview), Fish Shellfish Immunol., 2006, vol. 20, pp. 137–151.CrossRefGoogle Scholar
  36. 36.
    Dominguez, M., Takemura, A., and Tsuchiya, M., Effects of changes in environmental factors on the non-specific immune response of Nile tilapia, Oreochromis niloticus L., Aquacult. Res., 2005, vol. 36, no. 4, pp. 391–397.Google Scholar
  37. 37.
    Nair, R.M., George, K.C., Sanil, N.K., and Sobhana, K.S., Reticuloendothelial system of defense in Oreochromis mossambicus (Peters), Indian J. Fish, 2003, vol. 50, no. 2, pp. 139–147.Google Scholar
  38. 38.
    Parker, G.A. and Picut, C.A., Liver immunobiology, Toxicol. Pathol., 2005, vol. 33, pp. 52–62.CrossRefGoogle Scholar
  39. 39.
    Peyghan, R., Khadjeh, G.H., and Enayati, A., Effect of water salinity on total protein and electrophoretic pattern of serum proteins of grass carp, Ctenopharyngodon idella, Vet. Res. Forum, 2014, vol. 5, no. 3, pp. 225–229.Google Scholar
  40. 40.
    Press, C.M., Dannevig, B.H., and Landsverk, T., Immune and enzyme histochemical phenotypes of lymphoid and nonlymphoid cells within the spleen and head kidney of Atlantic salmon (Salmo salar L.), Fish Shellfish Immunol., 1994, vol. 4, pp. 79–93.CrossRefGoogle Scholar
  41. 41.
    Satheeshkumar, P., Ananthan, G., Senthilkumar, D., et al., Comparative investigation on haematological and biochemical studies on wild marine teleost fishes from Vellar estuary, southeast coast of India, Comp. Clin. Pathol., 2012, vol. 21, pp. 275–281.CrossRefGoogle Scholar
  42. 42.
    Saurabh, S. and Sahoo, P.K., Lysozyme: an important defense molecule of fish innate immune system, Aquat. Res., 2008, vol. 39, no. 3, pp. 223–239.CrossRefGoogle Scholar
  43. 43.
    Siwicki, A.K., Zakes, Z., Trapkowska, S., et al., Selected hematological and biochemical parameters of pikeperch Sander lucioperca (L.) from intensive culture, Arch. Pol. Fish., 2003, vol. 11, no. 1, pp. 17–22.Google Scholar
  44. 44.
    Tort, L., Balasch, J.C., and Mackenzie, S., Fish immune system. A crossroads between innate and adaptive responses, Immunologia, 2003, vol. 22, no. 3, pp. 277–286.Google Scholar
  45. 45.
    Uribe, C., Folch, H., Enriquez, R., and Moran, G., Innate and adaptive immunity in teleost fish: a review, Vet. Med., 2011, vol. 56, no. 10, pp. 486–503.CrossRefGoogle Scholar
  46. 46.
    Xie, Z., Niu, C., Zhang, Z., and Bao, L., Dietary ascorbic acid may be necessary for enhancing the immune response in Siberian sturgeon (Acipenser baerii), a species capable of ascorbic acid biosynthesis, Comp. Biochem. Physiol., 2006, vol. 145, pp. 152–157.CrossRefGoogle Scholar
  47. 47.
    Zapata, A., Diez, B., Cejalvo, T., et al., Ontogeny of the immune system of fish. review, Fish Shellfish Immunol., 2006, vol. 20, no. 2, pp. 126–136.CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  1. 1.Papanin Institute for Biology of Inland Waters, Russian Academy of SciencesBorokRussia
  2. 2.Demidov Yaroslavl State UniversityYaroslavlRussia
  3. 3.Yaroslavl Scientific Research Institute of Livestock Breeding and Forage Production, Federal Williams Research CenterMikhailovskyRussia

Personalised recommendations