Russian Journal of Organic Chemistry

, Volume 55, Issue 6, pp 883–885 | Cite as

Oxidative Cyclization of Lithium 4-Ethoxy-1,1,1-trifluoro-4-oxobut-2-en-2-olate

  • N. S. Boltacheva
  • P. A. Slepukhin
  • V. I. FilyakovaEmail author
  • V. N. Charushin
Short Communications


Diethyl 2,5-dihydroxy-2,5-bis(trifluoromethyl)tetrahydrofuran-3,4-dicarboxylate has been synthesized for the first time by reaction of lithium 4-ethoxy-1,1,1-trifluoro-4-oxobut-2-en-2-olate with manganese(III) acetate. The structure of its (2S*3S*4S*5S*) stereoisomer has been confirmed by X-ray analysis.


lithium 4-ethoxy-1,1,1-trifluoro-4-oxobut-2-en-2-olate manganese(III) acetate diethyl 2,5-dihydroxy-2,5-bis(trifluoromethyl)tetrahydrofuran-3,4-dicarboxylate crystal structure X-ray analysis 


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This study was performed using the facilities of the “Spectroscopy and Analysis of Organic Compounds” joint center (Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences).


This study was performed in the framework of state assignment no. AAAA-A19-119011790132-7.


  1. 1.
    Badanyan, Sh.O., Melikyan, G.G., and Mkrtchyan, D.A., Russ. Chem. Rev., 1989, vol. 58, p. 286. doi CrossRefGoogle Scholar
  2. 2.
    Slepukhin, P.A., Boltacheva, N.S., Filyakova, V.I., and Charushin, V.N., Russ. Chem. Bull., Int. Ed., 2009, vol. 58, p. 1228. doi CrossRefGoogle Scholar
  3. 3.
    Bräuer, G., Handbuch der Präparativen anorganischen Chemie, Stuttgart: Enke, 1981. Translated under the title Rukovodstvo po neorganicheskomu sintezu, Moscow: Mir, 1985, vol. 5, p. 1693.Google Scholar
  4. 4.
    Sheldrick, G.M., Acta Crystallogr., Sect. A, 2008. vol. 64, p. 112. doi CrossRefGoogle Scholar

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© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • N. S. Boltacheva
    • 1
  • P. A. Slepukhin
    • 1
  • V. I. Filyakova
    • 1
    Email author
  • V. N. Charushin
    • 1
  1. 1.Postovskii Institute of Organic Synthesis, Ural BranchRussian Academy of SciencesYekaterinburgRussia

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