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Russian Journal of Organic Chemistry

, Volume 54, Issue 8, pp 1250–1255 | Cite as

One-Pot Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazoles Using Catalytic System NaOH‒DMSO

  • V. E. Pankrat’eva
  • T. V. Sharonova
  • M. V. Tarasenko
  • S. V. Baikov
  • E. R. Kofanov
Article
  • 27 Downloads

Abstract

One-pot convenient process was developed for the production of 3,5-disubstituted 1,2,4-oxadiazoles by reaction of amidoximes with anhydrides or acyl chlorides in a system NaOH‒DMSO. The reaction proceeds at room temperature with high yields.

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • V. E. Pankrat’eva
    • 1
  • T. V. Sharonova
    • 1
  • M. V. Tarasenko
    • 2
  • S. V. Baikov
    • 3
  • E. R. Kofanov
    • 2
  1. 1.Transfer Center of Pharmaceutical TechnologyUshinski Yaroslavl State Pedagogical UniversityYaroslavlRussia
  2. 2.Yaroslavl State Technical UniversityYaroslavlRussia
  3. 3.St. Petersburg State UniversitySt. PetersburgRussia

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