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Synthesis of N-(Adamantan-1-yl)carbamides by Ritter Reaction from Adamantan-1-ol and Nitriles in the Presence of Cu-Catalysts

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Abstract

A selective synthesis of (Z)-N-(adamantan-1-yl)carbamides by the reaction of adamantan-1-ol and nitriles in the presence of Cu catalysts was carried out. Z-Conformation of amides is established basing on X-ray diffraction analysis and 2D NMR data.

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Authors and Affiliations

  1. Institute of Petrochemistry and Catalysis of the Russian Academy of Sciences, pr. Oktyabrya 141, Ufa, Bashkortostan, 450075, Russia

    A. R. Bayguzina, A. R. Lutfullina & R. I. Khusnutdinov

Authors
  1. A. R. Bayguzina
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  2. A. R. Lutfullina
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  3. R. I. Khusnutdinov
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Correspondence to A. R. Bayguzina.

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Original Russian Text © A.R. Bayguzina, A.R. Lutfullina, R.I. Khusnutdinov, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 8, pp. 1121–1126.

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Bayguzina, A.R., Lutfullina, A.R. & Khusnutdinov, R.I. Synthesis of N-(Adamantan-1-yl)carbamides by Ritter Reaction from Adamantan-1-ol and Nitriles in the Presence of Cu-Catalysts. Russ J Org Chem 54, 1127–1133 (2018). https://doi.org/10.1134/S1070428018080031

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  • DOI: https://doi.org/10.1134/S1070428018080031

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