Russian Journal of General Chemistry

, Volume 89, Issue 10, pp 1990–1997 | Cite as

Reactivity of Selected Mono- and Dimethylpyridines under Conditions of Oxidative Ammonolysis

  • P. B. VorobyevEmail author
  • A. P. Serebryanskaya


The reactivity of 3-methyl-, 4-methyl-, 2,3-dimethyl-, and 3,4-dimethylpyridines under the oxidative ammonolysis on vanadium oxide catalysts has been studied. The yield of monocyanopyridines has been related to the simulated values of the deprotonation enthalpy of methyl substituents being converted into the cyano group, both in the gas phase and under conditions simulating chemisorption at the acid center of the catalyst. Differences in the mechanism of conversion of the primary products of oxidative ammonolysis of 2,3- and 3,4-dimethylpyridines (2-cyano-3-methyl- and 4-cyano-3-methylpyridines) at elevated temperature have been revealed.


oxidative ammonolysis 3(4)-methylpyridines 2,3(3,4)-dimethylpyridines vanadium oxide catalysts 


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Conflict of Interests

No conflict of interest was declared by the authors.


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© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  1. 1.A.B. Bekturov Institute of Chemical SciencesAlmatyKazakhstan

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