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Russian Journal of General Chemistry

, Volume 89, Issue 8, pp 1595–1603 | Cite as

Functionalization of 2-Phosphoryl-Substituted Phenols

  • Yu. I. Rogacheva
  • D. V. BaulinEmail author
  • V. E. Baulin
  • A. Yu. Tsivadze
Article
  • 7 Downloads

Abstract

The nitration, bromination, diazo coupling, sulfonation, and alkylation of the aromatic ring of a series of 2-phosphoryl-substituted phenols have been studied for the first time. 2,6-Diphosphorylphenols have been obtained for the first time via 1,3-phosphorotropic phosphate-phosphonate rearrangement. The alkylation of 2-(diphenylphosphoryl)phenol at the hydroxy group with 2-bromo- and 2-chloroethanols has been studied under conventional heating and microwave irradiation conditions.

Keywords

2-phosphorylphenols electrophilic substitution 1,3-phosphate-phosphonate rearrangement 2,6-diphosphorylphenols 

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Notes

Funding

This study was performed under partial financial support by the Russian Foundation for Basic Research (project no. 19-03-00262) in the framework of state assignment for the Institute of Physiologically Active Compounds of the Russian Academy of Sciences.

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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • Yu. I. Rogacheva
    • 1
  • D. V. Baulin
    • 2
    Email author
  • V. E. Baulin
    • 1
    • 2
  • A. Yu. Tsivadze
    • 2
  1. 1.Institute of Physiologically Active CompoundsRussian Academy of SciencesChernogolovka, Moscow oblastRussia
  2. 2.Frumkin Institute of Physical Chemistry and ElectrochemistryRussian Academy of SciencesMoscowRussia

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