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Russian Journal of General Chemistry

, Volume 89, Issue 7, pp 1384–1387 | Cite as

Synthesis and Properties of Aminomethoxy Derivatives of 1-Hexylthioheptane

  • I. A. Jafarov
  • E. H. MammadbayliEmail author
  • A. D. Astanova
  • G. A. Abiyev
Article
  • 3 Downloads

Abstract

A series of new aminomethoxy derivatives of 1-hexylthioheptane have been synthesized via the Mannich reaction based on 1-hexylthioheptan-2-ol, secondary aliphatic and cyclic amines. Antimicrobial activity of the synthesized compounds has been studied in relation to gram-negative (E. coli and Pseudomonas aeruginosa), gram-positive (Staphylococcus aureus), sporogenous (anthracoid) bacteria, and yeast-like Candida fungi.

Keywords

hexylthioheptan-2-ol secondary amines Mannich reaction aminomethoxy derivatives of hexylthioheptane antiseptic activity 

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References

  1. 1.
    Jammi, S., Barua, P., Rout, L., Saha, P., and Punniyamujrthy, T., Tetrahedron Lett., 2008, vol. 49, p. 1484. doi  https://doi.org/10.1016/j.tetlet.2007.12.118 CrossRefGoogle Scholar
  2. 2.
    Kaur, P. and Wakode, S., Int. J. Sci. Res., 2016, vol. 5, no. 3, p. 762.Google Scholar
  3. 3.
    Subramaniapillai, S.G., J. Chem. Sci., 2013, vol. 125, no. 3, p. 467.CrossRefGoogle Scholar
  4. 4.
    Tramontini, M. and Angiolini, L., Tetrahedron, 1990, vol. 46, no. 6, p. 1791. doi  https://doi.org/10.1016/S0040-4020(01)89752-0 CrossRefGoogle Scholar
  5. 5.
    Goulioukina, N.S., Makukhin, N.N., and Beletskaya, I.P., Russ. Chem. Rev., 2016, vol. 85, no. 7, p. 667. doi  https://doi.org/10.1070/rcr4579 CrossRefGoogle Scholar
  6. 6.
    Roman, G., Eur. J. Med. Chem., 2015, vol. 89, p. 743. doi  https://doi.org/10.1016/j.ejmech.2014.10.076 CrossRefGoogle Scholar
  7. 7.
    Bogdanov, A.V., Vazykhanova, A.M., Khasiyatullina, N.R., Krivolapov, D.B., Dobrynin, A.B., Voloshina, A.D., and Mironov, V.F., Chem. Heterocycl. Compd., 2016, vol. 52, no. 1, p. 25. doi  https://doi.org/10.1007/s10593-016-1826-6 CrossRefGoogle Scholar
  8. 8.
    Hajiyeva, G.E., Mammadbayli, E.H., Ibrahimov, S.I., and Talybov, G.M., Proc. Petrochem. Oil Ref., 2017, vol. 18, no. 4, p. 331.Google Scholar
  9. 9.
    Mammadbayli, E.H., Jafarov, I.A., Qahramanova, S.N., and Suleymanova, E.I., Petroleum Chem., 2018, vol. 58, no. 3, p. 274. doi  https://doi.org/10.7868/S0028242118020168 CrossRefGoogle Scholar
  10. 10.
    Mamedbeyli, E.H., Jafarov, I.A., Talybov, G.M., Mirzoeva, M.A., Iskenderova, K.O., and Hajizade, A.N., Russ. J. Gen. Chem., 2017, vol. 87, no. 4, p. 713. doi  https://doi.org/10.1134/S107036321704009 CrossRefGoogle Scholar
  11. 11.
    Yur’ev, Yu.K., Prakticheskie raboty po organicheskoi khimii, (Practical Work in Organic Chemistry), Moscow: Mosk. Univ 1961.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • I. A. Jafarov
    • 1
  • E. H. Mammadbayli
    • 2
    Email author
  • A. D. Astanova
    • 1
  • G. A. Abiyev
    • 3
  1. 1.Azerbaijan Pedagogical UniversityBakuAzerbaijan
  2. 2.Institute of Petrochemical Processes of the National Academy of Sciences of AzerbaijanBakuAzerbaijan
  3. 3.Azerbaijan Medical UniversityBakuAzerbaijan

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