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Russian Journal of General Chemistry

, Volume 89, Issue 6, pp 1221–1224 | Cite as

Synthesis and Antimicrobial Activity of 3-{2-[(1-Aryl-1H-1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles

  • K. Santhosh Kumar
  • S. Mohanty
  • G. P. Reddy
  • V. Siddaiah
  • J. D. Lilakar
  • G. L. GoudEmail author
Article
  • 13 Downloads

Abstract

A novel series 3-{2-[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]-5-fluorophenyl}isoxazoles derivatives is synthesized from 1-(5-fluoro-2-hydroxyphenyl)ethanone. All the synthesized compounds are characterized by IR, 1H and 13C NMR, and mass spectral data, and tested for their in vitro antimicrobial activity against bacterial and fungal organisms.

Keyword

isoxazole 1,2,3-triazole antimicrobial activity Click reaction 

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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • K. Santhosh Kumar
    • 1
    • 2
  • S. Mohanty
    • 1
  • G. P. Reddy
    • 1
  • V. Siddaiah
    • 2
  • J. D. Lilakar
    • 3
  • G. L. Goud
    • 4
    Email author
  1. 1.Process Research and DevelopmentDr. Reddy’s Laboratories Ltd.Bollaram, MedakIndia
  2. 2.Department of Organic Chemistry and FDWAndhra UniversityVisakhapatnamIndia
  3. 3.PI Industries LimitedUdaipurIndia
  4. 4.Spectrum BiosciencesHyderabadIndia

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