Methyl Trifluoropyruvate in Cyclocondensation Reactions with N-Substituted Ureas
- 5 Downloads
The transformations of methyl trifluoropyruvate in cyclocondensation reactions with N-substituted ureas, leading to 3-substituted 5-hydroxy- or 5-methoxy-5-trifluoromethylimidazolidine-2,4-diones, were studied. The possibility of using 5-hydroxy-3-(prop-2-in-1-yl)-5-trifluoromethylimidazolidine-2,4-dione for modifying phenothiazine with a copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition was shown.
Keywordsmethyl trifluoropyruvate N-substituted ureas 5-trifluoromethylimidazolidine-2,4-diones phenothiazine 1,3-dipolar cycloaddition
Unable to display preview. Download preview PDF.
- 6.Rostovtsev, V.V., Green, L.G., Fokin, V.V., and Sharpless, K.B., Angew. Chem. Int. Ed., 2002, vol. 41, no. 14, p. 2596. doi https://doi.org/10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4 CrossRefGoogle Scholar