Russian Journal of General Chemistry

, Volume 89, Issue 1, pp 153–156 | Cite as

Methyl Trifluoropyruvate in Cyclocondensation Reactions with N-Substituted Ureas

  • V. B. Sokolov
  • A. Yu. AksinenkoEmail author
Letters to the Editor


The transformations of methyl trifluoropyruvate in cyclocondensation reactions with N-substituted ureas, leading to 3-substituted 5-hydroxy- or 5-methoxy-5-trifluoromethylimidazolidine-2,4-diones, were studied. The possibility of using 5-hydroxy-3-(prop-2-in-1-yl)-5-trifluoromethylimidazolidine-2,4-dione for modifying phenothiazine with a copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition was shown.


methyl trifluoropyruvate N-substituted ureas 5-trifluoromethylimidazolidine-2,4-diones phenothiazine 1,3-dipolar cycloaddition 


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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  1. 1.Institute of Physiologically Active Compounds of the Russian Academy of SciencesChernogolovkaRussia

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