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Russian Journal of General Chemistry

, Volume 88, Issue 11, pp 2442–2444 | Cite as

1-(3,3-Diethoxypropyl)-1-[(dihexylphosphoryl)methyl]-3-phenylurea in the Synthesis of 4-Aryl-Substituted Tetrahydropyrimidin-2-ones

  • L. I. VagapovaEmail author
  • K. V. Matylitskii
  • A. R. Burilov
  • A. R. Garifzyanov
  • M. A. Pudovik
Letters to the Editor
  • 6 Downloads

Abstract

First specimens of 4-aryl-substituted tetrahydropyrimidin-2(1H)-ones containing a phosphoryl group were obtained through the reaction of 1-(3,3-diethoxypropyl)-1-[(dihexylphosphoryl)methyl]-3-phenylurea with resorcinol and its derivatives in the presence of trifluoroacetic acid.

Keywords

aminophosphine oxides ureidoacetals condensation resorcinol 

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References

  1. 1.
    Kappe, C.O., Acc. Chem. Res., 2000, vol. 33, p. 879. doi 10.1021/ar000048hCrossRefGoogle Scholar
  2. 2.
    Jetti, S.R., Upadhyaya, A., and Jain, S., Med. Chem. Res., 2014, vol 23, p. 4356. doi 10.1007/s00044-014-0988-yCrossRefGoogle Scholar
  3. 3.
    Amir, M., Javed, S.A., and Kumar, H., Acta Pharm., 2008, vol. 58, p. 467. doi 10.2478/v10007-008-0028-xCrossRefGoogle Scholar
  4. 4.
    Soumyanarayanan, U., Bhat, V.G., Kar, S.S., and Mathew, J.A., Org. Med. Chem. Lett., 2012, vol. 2, no. 23, p. 1. doi 10.1186/2191-2858-2-23Google Scholar
  5. 5.
    Gong, D., Zhang, L., and Yuan, C., Heteroatom Chem., 2003, vol. 14, no. 1, p. 13. doi 10.1002/hc.10058CrossRefGoogle Scholar
  6. 6.
    Zigeuner, G. and zur Hausen, M., Monatsh. Chem., 1961, vol. 92, p. 278. doi 10.1007/BF01153882CrossRefGoogle Scholar
  7. 7.
    Vagapova, L.I., Voronina, J.K., Sykaev, V.V., Burilov, A.R., Garifzyanov, A.R., and Pudovik, M.A., Mendeleev Commun., 2018, vol. 28, no. 4, p. 398. doi 10.1016/j.mencom.2018.07.019CrossRefGoogle Scholar
  8. 8.
    Vagapova, L.I., Amirova, L.R., Burilov, A.R., Garifzyanov, A.R., Pudovik, M.A., and Kharlampidi, Kh.E., Russ. J. Org. Chem., 2014, vol. 50, no. 6, p. 778. doi 10.1134/S1070428014060025CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • L. I. Vagapova
    • 1
    Email author
  • K. V. Matylitskii
    • 2
  • A. R. Burilov
    • 1
  • A. R. Garifzyanov
    • 3
  • M. A. Pudovik
    • 1
  1. 1.A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific CenterRussian Academy of SciencesKazan, TatarstanRussia
  2. 2.Kazan National Research Technological UniversityKazan, TatarstanRussia
  3. 3.Kazan (Volga Region) Federal UniversityKazan, TatarstanRussia

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