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Russian Journal of General Chemistry

, Volume 88, Issue 11, pp 2438–2441 | Cite as

Synthesis of Hybrid Pharmacophores Based on Adducts of N-Sulfinylaniline and Norbornadiene

  • O. A. Tevs
  • Ya. V. Veremeychik
  • O. A. LodochnikovaEmail author
  • V. V. Plemenkov
  • I. A. Litvinov
Letters to the Editor
  • 8 Downloads

Abstract

Acylation of benzothiazinesulfonamides obtained by the oxidation of N-sulfinylaniline and norbornadiene adducts with acid chlorides and carboxylic anhydrides led to the formation of N-acylated sulfonamide hybrid pharmacophores. Molecular and crystal structure of the acylated products was established by X-ray diffraction method.

Keywords

sulfonamides acylation hybrid pharmacophores 

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • O. A. Tevs
    • 1
  • Ya. V. Veremeychik
    • 1
  • O. A. Lodochnikova
    • 2
    • 3
    Email author
  • V. V. Plemenkov
    • 3
  • I. A. Litvinov
    • 2
    • 4
  1. 1.Kant Baltic Federal UniversityKaliningradRussia
  2. 2.A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific CenterRussian Academy of SciencesKazan, TatarstanRussia
  3. 3.Butlerov Institute of ChemistryKazan Federal (Volga Region) UniversityKazan, TatarstanRussia
  4. 4.Tupolev Kazan National Research Technical University (KAI)Kazan, TatarstanRussia

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