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Russian Journal of Coordination Chemistry

, Volume 44, Issue 12, pp 824–830 | Cite as

Crystal Structure and Anti-kidney Cancer Activity of Two Novel Coordination Polymers {[Cu2(DCTP)2](H2O)}n and {[Zn5(NTB)4(DMF)2](NH2NMe2)(DMF)3}n

  • F. LinEmail author
  • F. Q. Dong
  • X. Q. Chen
  • Q. X. Zhou
  • Y. Zhou
  • B. C. Chen
Article
  • 6 Downloads

Abstract

Two new coordination polymers, namely {[Cu2(DCTP)2](H2O)}n (I) (H2DCTP = 4'-(3,5-dicarboxyphenyl)-4,2':6',4''-terpyridine) and {[Zn5(NTB)4(DMF)2](H2NMe2)2(DMF)3}n (II) (H3NTB = 4,4′,4″-nitrilotribenzoic acid, DMF = N,N-dimethylformamide), have been successfully constructed under solvothermal conditions. The structures of two complexes have been successfully determined by single crystal X-ray diffraction (CIF files CCDC nos. 1852377 (I) and 1852378 (II)). In addition, in vitro antitumor activity of compounds I and II on four human kidney cancer cells (GRC-1, A-498, ACHN and 786-P) was further determined and the results show that the two compounds showed promising activity.

Keywords:

coordination polymer X-ray diffraction kidney cancer cell 

Notes

ACKNOWLEDGMENTS

This research was supported by Zhejiang Provincial Natural Science Foundation of China (no. LY14H050006).

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • F. Lin
    • 1
    • 2
    Email author
  • F. Q. Dong
    • 3
    • 4
  • X. Q. Chen
    • 1
  • Q. X. Zhou
    • 1
  • Y. Zhou
    • 1
  • B. C. Chen
    • 1
  1. 1.Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouP.R. China
  2. 2.Department of Nephrology, Shenzhen University General HospitalShenzhenP.R. China
  3. 3.Department of Cardiology, Shenzhen University General HospitalShenzhenP.R. China
  4. 4.Shenzhen University Clinical Medical AcademyShenzhenP.R. China

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