Russian Journal of Bioorganic Chemistry

, Volume 45, Issue 6, pp 438–450 | Cite as

Application of Natural Polysaccharides in Pharmaceutics

  • M. V. KhvostovEmail author
  • T. G. Tolstikova
  • S. A. Borisov
  • A. V. Dushkin


Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.


polysaccharides increased bioavailability pullulan alginates hyaluronic acid dextrans pectin chitosan arabinogalactan 



Conflict of Interests.

The authors declare that they have no conflict of interest.

Statement on the Welfare of Animals.

This article does not contain any studies involving animals performed by any of the authors.

Statement of Compliance with Standards of Research Involving Humans as Subjects.

This article does not contain any studies involving humans as subjects of research.


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© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • M. V. Khvostov
    • 1
    • 2
    Email author
  • T. G. Tolstikova
    • 1
    • 2
    • 3
  • S. A. Borisov
    • 1
  • A. V. Dushkin
    • 3
  1. 1.Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of SciencesNovosibirskRussia
  2. 2.Novosibirsk State UniversityNovosibirskRussia
  3. 3.Institute of Solid State Chemistry and Mechanochemistry, Siberian Branch, Russian Academy of SciencesNovosibirskRussia

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