Abstract
Polarization of 3He gas by means of optical pumping is well known since the early 1960s with first applications in fundamental physics. Some thirty years later it was discovered, that one can use hyperpolarized 3He as contrast agent for magnetic resonance imaging of the lung. The wide interest in this new method made it necessary to find ways of polarizing 3He in large quantities with high polarization degrees. A high performance polarizing facility has been developed at the University of Mainz, designed for centralized production of hyperpolarized 3He gas. We present the Mainz concept as well as some examples of numerous applications of spin polarized 3He in fundamental research and medical applications.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
F. D. Colegrove, L. D. Schearer, and G. K. Walters, Phys. Rev. 132, 2561 (1963).
P. J. Nacher and M. Leduc, J. Phys. 46, 2057 (1985).
B. Blankleider and R. M. Woloshyn, Phys. Rev. C 29, 538 (1984).
J. Krimmer et al., Nucl. Instr. Methods Phys. Res. A 611, 18 (2009).
J. Krimmer et al., Nucl. Instr. Methods Phys. Res. A 648, 35 (2011).
W. Heil et al., Nucl. Instr. Methods Phys. Res. A 485, 551 (2002).
A. Ioffe, E. Babcock, and Th. Gutberlet, J. Phys., Conf. Ser. 294, 011001 (2011).
M. S. Albert et al., Nature 370, 199 (1994).
M. Ebert et al., The Lancet 347, 1297 (1996).
M. Leduc and P. J. Nacher, CP770, At. Phys. 19, 381 (2005).
E. W. Otten, Europhys. News 35, 16 (2004).
M. Terekhov et al., J. Magn. Res. Imag. 32, 887 (2010).
M. Batz et al., J. Res. Nat. Inst. Stand. Technol. 110, 293 (2005).
J. Schmiedeskamp et al., Eur. Phys. J. D 38, 427 (2006).
S. Hiebel et al., J. Magn. Res. 204, 37 (2010).
M. Güldner et al., J. Phys., Conf. Ser. 294, 012006 (2011).
Z. Salhi et al., Magn. Res. Med. 67, 1758 (2012).
C. Mrozik et al., J. Phys., Conf. Ser. 294, 012007 (2011).
Manufacturing authorisation No. 2010/128/55/M by the State Office for Social Matters, Youth and Pensions, Rhineland Palatinate, Germany.
T. E. Parker, Metrologia 47, 1 (2010).
F. Allmendinger et al., Hyperf. Interact. 215, 15 (2013).
V. A. Kostelecký and C. D. Lane, Phys. Rev. D 60, 116010 (1999).
J. F. Moody and F. Wilczek, Phys. Rev. D 30, 130 (1984).
Th. Schmidt, Zeitschrift für Physik A 106, 358 (1937).
M. A. Rosenberry and T. E. Chupp, Phys. Rev. Lett. 86, 22 (2001).
C. Gemmel et al., Eur. Phys. J. D 57, 303 (2010).
S. M. Kay, in Fundamentals of Statistical Signal Processing: Estimation Theory, Vol. 1 (Prentice Hall, New Jersey, 1993).
G. D. Cates, S. R. Schaefer, and W. Happer, Phys. Rev. A 37, 2887 (1988).
M. Burghoff et al., Neurol. Clin. Neurophys. 67, 1 (2004).
A. Schnabel et al., Neurol. Clin. Neurophys. 71, 1 (2004).
C. Gemmel et al., Phys. Rev. D 82, 111901 (2010).
F. Allmendinger et al., in press.
I. Antoniadis et al., Comptes Rendus Physique 12, 755 (2011).
M. Burghoff et al., J. Phys., Conf. Ser. 295, 012017 (2011).
K. Tullney et al., Phys. Rev. Lett. 111, 100801 (2013).
W. Heil et al., Ann. Phys. 525, 519 (2013).
Author information
Authors and Affiliations
Corresponding author
Additional information
The article is published in the original.
Rights and permissions
About this article
Cite this article
Karpuk, S., Allmendinger, F., Burghoff, M. et al. Spin polarized 3He: From basic research to medical applications. Phys. Part. Nuclei 44, 904–908 (2013). https://doi.org/10.1134/S1063779613060105
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1063779613060105