Colloid Journal

, Volume 80, Issue 6, pp 667–675 | Cite as

Disaggregation of Magnesium Octa[(4'-Benzo-15-Crown-5)Oxy]Phthalocyaninate in Aqueous Micellar Solutions of Alkyltriphenylphosphonium Bromide

  • T. G. MovchanEmail author
  • A. Yu. Chernyad’ev
  • E. V. Plotnikova
  • A. A. Averin
  • A. Yu. Tsivadze
  • V. E. Baulin


The behavior of magnesium octa[(4'-benzo-15-crown-5)oxy]phthalocyaninate (Mgcr8Pc) in aqueous micellar solutions of alkyltriphenylphosphonium bromides (CnTPPBs), where n = 8, 12, 14, and 16, has been studied by means of electronic absorption spectroscopy and measurements of fluorescence photophysical characteristics. Intense bands of absorption (λmax = 683 nm) and fluorescence (λmax = 694 nm) of Mgcr8Pc in CnTPPB micellar solutions are characterized by monoexponential decay of intensity (lifetime of 5.98–6.29 ns) and indicate that magnesium phthalocyaninate has the monomeric form. The disaggregation of Mgcr8Pc in the presence of CnTPPBs provides an opportunity to use aqueous micellar solutions containing this metallophthalocyane in photodynamic therapy, because it is the monomeric form of Mgcr8Pc that generates singlet oxygen molecules, which kill tumor cells.



Fluorescence measurements were carried out using the facilities of the Center for Collective Use of Physical Methods of Investigation, A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences.

The study was carried out within the framework of a state assignment (project no. 0081-2014-0015) and supported by the Russian Foundation for Basic Research (project no. 18-03-00743).


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Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • T. G. Movchan
    • 1
    Email author
  • A. Yu. Chernyad’ev
    • 1
  • E. V. Plotnikova
    • 1
  • A. A. Averin
    • 1
  • A. Yu. Tsivadze
    • 1
  • V. E. Baulin
    • 1
    • 2
  1. 1.Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of ScienceMoscowRussia
  2. 2.Institute of Physiologically Active Substances, Russian Academy of SciencesChernogolovkaRussia

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