Russian Journal of Genetics

, Volume 55, Issue 2, pp 267–270 | Cite as

Polymorphism of the Hypervariable Region of the csd Gene in the Apis mellifera L. Population in Southern Urals

  • M. D. KaskinovaEmail author
  • A. R. Gataullin
  • E. S. Saltykova
  • L. R. Gaifullina
  • A. V. Poskryakov
  • A. G. Nikolenko


In honey bees, sex is determined by an allelic combination of the csd gene. Low allelic diversity for the csd gene leads to a loss of colony strength due to the appearance of nonviable diploid drones from eggs homozygous for the csd gene. Therefore, there is a need in beekeeping to identify and monitor the allelic diversity of the csd gene. In this paper, we present the results of the polymorphism analysis of the hypervariable region of the csd gene in the local population of Apis melliferamellifera L. in the Southern Urals. Among 42 amino acid sequences encoded by alleles of the hypervariable region, 20 alleles were identified, five of which were previously unknown. It was shown that the allelic diversity for the csd gene for the studied population corresponds to those known for other populations of A. mellifera L.


Apis mellifera L. DNA sequencing honeybee genetics csd gene 



We express our gratitude to Cand. Sci. (Biol.) V.O. Kugeiko for providing bees for research.

This work was supported by the grant of the Russian Foundation for Basic Research no. 17-44-020648 using the resources of the Shared Use Center of the Ufa Federal Research Center of the Russian Academy of Sciences and the Shared Use Center Insect Collection of the Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences.


Conflict of interests. The authors declare that they have no conflict of interest.

Statement on the welfare of animals. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.


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Copyright information

© Pleiades Publishing, Inc. 2019

Authors and Affiliations

  • M. D. Kaskinova
    • 1
    Email author
  • A. R. Gataullin
    • 1
  • E. S. Saltykova
    • 1
  • L. R. Gaifullina
    • 1
  • A. V. Poskryakov
    • 1
  • A. G. Nikolenko
    • 1
  1. 1.Institute of Biochemistry and Genetics, Ufa Federal Research Center, Russian Academy of SciencesUfaRussia

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