Russian Journal of Genetics

, Volume 54, Issue 12, pp 1416–1428 | Cite as

Emerging Potential of Cancer Therapy—Binary Direct Interactions of Cancer and Stromal Cells

  • I. V. AlekseenkoEmail author
  • G. S. Monastyrskaya
  • E. D. Sverdlov


The review attempts to discuss the interaction of cancer cells and cells of the tumor microenvironment as well as the possibility of using them as a target for antitumor therapy.


cancer tumor microenvironment immune checkpoint molecules cancer-associated fibroblasts pancreas 



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Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • I. V. Alekseenko
    • 1
    Email author
  • G. S. Monastyrskaya
    • 1
  • E. D. Sverdlov
    • 1
  1. 1.Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of SciencesMoscowRussia

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