Theoretical Foundations of Chemical Engineering

, Volume 53, Issue 5, pp 939–944 | Cite as

Analysis of Extraction Chromatographic Separation of a Binary Mixture in a Series of Multistage Columns

  • A. E. KostanyanEmail author
  • M. M. Martynova


Two processes of multistage extraction chromatographic separation of components (with and without recycling) are theoretically studied under various conditions of loading of a mixture to be separated to the apparatus. A mathematical description of the separation processes is presented. It is shown that the separation of components in the process with recycling requires an order of magnitude fewer equilibrium stages than separation in the process without recycling. Moreover, the productivity of the process with recycling, which is determined by the duration of loading to the apparatus, is an order of magnitude higher.


preparative liquid–liquid chromatography multistage extraction mathematical modeling of separation processes 



This work was supported by the Russian Foundation for Basic Research (project no. 18-33-00081 mol_a).


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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  1. 1.Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of SciencesMoscowRussia

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