Batch Reactive Distillation in Bromodifluoroacetic Acid Synthesis Technology

  • E. V. LupachevEmail author
  • A. V. Polkovnichenko
  • S. Ya. Kvashnin
  • V. A. Lotkhov
  • N. N. KulovEmail author


A catalytic distillation process reacting in a column bottom was experimentally studied for the transesterification of methyl and ethyl esters of bromodifluoroacetic acid with trifluoroacetic acid. Sulfuric acid was used as a catalyst. Experiments were performed at different column bottom heat duties. As a result of the experiments, we had bromodifluoroacetic acid with a purity above 97.0 mol % at a product yield of 87.4%.


catalytic distillation transesterification fluoroorganic acids fluororganic esters bromodifluoroacetic acid 



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© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  1. 1.Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of SciencesMoscowRussia
  2. 2.MIREA Russian Technological University (Institute of Fine Chemical Technologies)MoscowRussia

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