Russian Journal of Physical Chemistry A

, Volume 92, Issue 4, pp 714–718 | Cite as

Association Constants in the Bovine Serum Albumin/Human Serum Albumin–Tween 20 System in Aqueous Solutions

  • I. M. Vlasova
  • A. A. Vlasov
  • G. R. Grapendaal
  • A. M. Saletskii
Physical Chemistry of Solutions
  • 14 Downloads

Abstract

The association constants in the bovine serum albumin/human serum albumin–Tween 20 system are determined in aqueous solutions at pH 3.5–8.0 by means of nonpolarized fluorescence and protein fluorescence quenching. It is found that the most efficient association of serum albumin molecules with Tween 20 micelles occurs at pH 5.0 near the isoelectric points of proteins.

Keywords

bovine serum albumin human serum albumin Tween 20 fluorescence quenching association constants 

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • I. M. Vlasova
    • 1
    • 2
  • A. A. Vlasov
    • 1
  • G. R. Grapendaal
    • 1
  • A. M. Saletskii
    • 1
  1. 1.Faculty of PhysicsMoscow State UniversityMoscowRussia
  2. 2.Center for Theoretical Problems of Physicochemical PharmacologyRussian Academy of SciencesMoscowRussia

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