Journal of Structural Chemistry

, Volume 59, Issue 7, pp 1688–1690 | Cite as

Molecular and Crystal Structure of a Novel Mannich Quaternary Salt: 3-(Dimethylamino)-1-p-Tolylpropan-1-One Hydrochloride

  • A. O. AyeniEmail author
  • G. M. Watkins
  • E. C. Hosten


A novel Mannich base is synthesized by the condensation of 4-methylacetophenone and dimethylamine hydrochloride in the presence of formaldehyde. The molecular and crystal structure of the title compound is confirmed by 1H, 13C NMR and IR spectroscopy, and single crystal X-ray diffraction.


Mannich base aminomethylation acetophenones NMR single crystal X-ray diffraction analysis 


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© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  1. 1.Department of ChemistryRhodes UniversityGrahamstownSouth Africa
  2. 2.Department of ChemistryObafemi Awolowo UniversityIle IfeNigeria
  3. 3.Department of ChemistryNelson Mandela Metropolitan UniversityPort ElizabethSouth Africa

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