, Volume 63, Issue 5, pp 798–804 | Cite as

Continuous In Vivo Monitoring of the Oxygen Concentration in Tissues

  • S. N. LetutaEmail author
  • A. T. Ishemgulov
  • U. G. Letuta
  • S. N. Pashkevich

Abstract—The kinetics of delayed fluorescence and phosphorescence of xanthene dyes in mouse tissues under the pulse-periodic excitation of molecules was studied in vivo and in vitro. The advantages of continuous monitoring of oxygen content in tissues by the kinetics of delayed fluorescence caused by singlet–triplet annihilation of singlet oxygen with triplet excitation of fluorophore are demonstrated. A method is proposed for determining the time of recovery of the concentration of oxygen consumed in tissues in vivo and in vitro during photodynamic processes.

Keywords: singlet oxygen  tissues xanthene dyes delayed luminescence 



The work was supported by the Ministry of Science and Higher Education of the Russian Federation, project no. 3.6358.2017/BCh, and the Russian Foundation for Basic Research, project no. 17-32-50051.


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Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • S. N. Letuta
    • 1
    Email author
  • A. T. Ishemgulov
    • 1
  • U. G. Letuta
    • 1
  • S. N. Pashkevich
    • 1
  1. 1.Orenburg State UniversityOrenburgRussia

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