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Applied Biochemistry and Microbiology

, Volume 54, Issue 5, pp 474–477 | Cite as

Medical Materials Based on Chitosan Succinamide–Glycerol Systems

  • M. V. Bazunova
  • L. A. Sharafutdinova
  • R. Yu. Lazdin
  • V. V. Chernova
  • D. N. Mixonov
  • V. P. Zakharov
Article

Abstract

The conditions to obtain materials with elastic-viscous properties based on chitosan succinamide have been studied. A decreased polymer content and a transition from visco-elastic liquids to elastic-viscous systems were shown upon the addition of glycerol to an aqueous solution of chitosan succinamide. The systemic response, biological compatibility, and dynamics of bioresorbability of the obtained materials were studied during implantation in laboratory animals.

Keywords

chitosan succinamide glycerol rheological properties storage modulus loss modulus biocompatibility 

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References

  1. 1.
    Andreeva, A.S., Fomenkov, A.I., Islamov, A.Kh., Kuklin, A.I., Filippova, O.E., and Khokhlov, A.R., Polym. Sci. Ser. A, 2005, vol. 47, no. 2, pp. 194–201.Google Scholar
  2. 2.
    Philippova, O.E. and Korchagina, E.V., Polym. Sci. Ser. A, 2012, vol. 54, no. 7, pp. 552–572.CrossRefGoogle Scholar
  3. 3.
    Grigorieva, M.V., Biotechnologiya, 2011, vol. 4, no. 2, pp. 9–23.Google Scholar
  4. 4.
    Lan, C., Niu, G.C., Chang, S.J., Yao, C.-H., and Kuo, S.M., Biomed. Eng. Appl. Basis Commun., 2011, vol. 23, no. 1, pp. 51–62.CrossRefGoogle Scholar
  5. 5.
    Adila, S.N. and Suyatma, N.E., in Biology, Environment And Chemistry IPCBEE. Materials of 4th International Conference, Singapore: IACSIT Press, 2013, vol. 58, no. 6, pp. 27–31.Google Scholar
  6. 6.
    Bazunova, M.V., Shurshina, A.S., Chernova, V.V., and Kulish, E.I., Russ. J. Phys. Chem. B, 2016, vol. 10, no. 6, pp. 1014–1021.CrossRefGoogle Scholar
  7. 7.
    Bazunova, M.V., Valiev, D.R., Tukhvatullin, R.F., and Kulish, E.I., Nauch.-Tekhn. Vestn. Povolzh’ya, 2015, no. 2, pp. 30–32.Google Scholar
  8. 8.
    Fomina, V.I., Malinkina, O.N., Gegel’, N.O., Abramov, A.Yu., and Shipovskaya, A.B., Izv. Sarat. Univ., Nov. Ser., Ser. Khim. Biol. Ekol., 2015, vol. 15, no. 1, pp. 28–36.Google Scholar
  9. 9.
    Shekhter, A.B. and Serov, V.V., Vospalenie. Rukovodstvo dlya vrachei (Inflammation. A Guide for Doctors), Serov, V.V and Paukov, V.S., Eds., Moscow: Meditsina, 1995.Google Scholar
  10. 10.
    Vasconcelos, D.P., Fonseca, A.C., Costa, M., Amaral, I.F., Barbosa, M.A., Aguas, A.P., and Barbosa, J.N., Biomaterials, 2013, vol. 34, no. 38, pp. 9952–9959.CrossRefPubMedGoogle Scholar
  11. 11.
    Martins, A.F., Borges, N.C., Coutinho, P.V., Lemes, A.R., Silva, A.S., Barbosa, R.K., and Paulo, N.M., Acta Cir. Bras., 2015, vol. 30, no. 10, pp. 675–680.CrossRefPubMedGoogle Scholar

Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • M. V. Bazunova
    • 1
  • L. A. Sharafutdinova
    • 1
  • R. Yu. Lazdin
    • 1
  • V. V. Chernova
    • 1
  • D. N. Mixonov
    • 1
  • V. P. Zakharov
    • 1
  1. 1.Bashkir State UniversityUfaRussia

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