Applied Biochemistry and Microbiology

, Volume 54, Issue 5, pp 496–500 | Cite as

Antimicrobial Activity of Silver Nanoparticles in a Carboxymethyl Chitin Matrix Obtained by the Microwave Hydrothermal Method

  • V. A. AlexandrovaEmail author
  • L. N. Shirokova
  • V. S. Sadykova
  • A. E. Baranchikov


Silver nanoparticles have been obtained in a matrix of 6-O-carboxymethyl chitin in the presence of D-glucose as a reducing agent by microwave hydrothermal synthesis. The TEM results show that the silver nanoparticles have a spherical shape; the particle size range is 3–20 nm. The resulting colloidal solution of silver nanoparticles had a strong bacterial effect on gram-positive bacteria Staphylococcus aureus ATCC 21027 (=209 P), Bacillus subtilis ATCC 6633, and, to a lesser extent, on gram-negative bacteria Escherichia coli АТСС 25922. The synthesized silver nanoparticles showed pronounced fungistatic activity against A. niger INA 00760.


microwave hydrothermal synthesis silver nanoparticles carboxymethyl chitin bactericidal activity 


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Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • V. A. Alexandrova
    • 1
    Email author
  • L. N. Shirokova
    • 1
  • V. S. Sadykova
    • 2
  • A. E. Baranchikov
    • 3
  1. 1.A.V. Topchiev Institute of Petrochemical SynthesisRussian Academy of SciencesMoscowRussia
  2. 2.G.F. Gause Institute of New AntibioticsMoscowRussia
  3. 3.N.S. Kurnakov Institute of General and Inorganic ChemistryRussian Academy of SciencesMoscowRussia

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