Journal of Assisted Reproduction and Genetics

, Volume 21, Issue 4, pp 103–107 | Cite as

Monozygotic Twins and Triplets in Association with Blastocyst Transfer

  • John K. Jain
  • Robert Boostanfar
  • Cristin C. Slater
  • Mary M. Francis
  • Richard J. Paulson


Purpose: To compare the incidence of monozygotic twins following blastocyst versus day-3 embryo transfer (ET).

Methods: A retrospective analysis of the outcome of assisted reproductive technology (ART) cycles utilizing blastocyst ET during 1999–2000 was compared to a similar group of patients undergoing day-3 ET during 1997–1998.

Results: Blastocyst ET was used in 75 cycles with 2.0 ± 2 embryos transferred. The comparison group consisted of 90 cycles with day-3 ET and 3.0 ± 2 embryos transferred.

Conclusions: High pregnancy rates are maintained with blastocyst ET even though fewer embryos are transferred. The rate of monozygotic twins is higher with blastocyst ET than with day-3 ET. This increase may partially negate the benefit of reduced high-order multiple gestations attributed to blastocyst ET.

Blastocyst in vitro fertilization monozygotic twins multiple pregnancies 


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Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • John K. Jain
    • 1
  • Robert Boostanfar
    • 1
  • Cristin C. Slater
    • 1
  • Mary M. Francis
    • 1
  • Richard J. Paulson
    • 1
  1. 1.Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and GynecologyUniversity of Southern California Keck School of MedicineLos Angeles

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