Abstract
The reaction of benzimidazo[1,2-b]isoquinolin-11(5H)-one with activated olefins has been studied. The derivatives of 3,10-dioxo-3H,10H-benzimidazo[1,2,3-ij]benzo[c][1,8]naphthyridine formed are the result of an initial Michael reaction at C(6) followed by intramolecular heterocyclization.
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Potikha, L.M., Shkilna, N.V., Kisil, V.M. et al. Condensed Isoquinolines. 18. Enamine Properties of Benzimidazo[1,2-b]isoquinolin-11(5H)-one in the Michael Reaction. Chemistry of Heterocyclic Compounds 40, 1179–1184 (2004). https://doi.org/10.1023/B:COHC.0000048292.31018.2b
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DOI: https://doi.org/10.1023/B:COHC.0000048292.31018.2b