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Chemistry of Heterocyclic Compounds

, Volume 40, Issue 7, pp 938–943 | Cite as

Reactions of 2-Amino-4-methyl-6-(2-pyridyl)- and 2-Amino-4-methyl-6-phenyl-7,8-dihydroindazolo[4,5-d]thiazoles with Aldehydes

  • I. Strakova
  • M. Petrova
  • A. Strakovs
Article
  • 70 Downloads

Abstract

The reaction of 2-amino-4-methyl-6-(2-pyridyl)-7,8-dihydroindazolo[4,5-d]thiazole, obtained by treating 3-methyl-4-oxo-1-(2-pyridyl)-4,5,6,7-tetrahydroindazole with pyridinium bromide perbromide and then with thiourea, and 2-amino-4-methyl-6-phenyl-7,8-dihydroindazolo[4,5-d]thiazole with 4-bromo-, 4-fluoro-, 4-dimethylamino-, 4-methoxy-, 3,4-dimethoxy-, and 3,4-methylenedioxybenzaldehydes, furfural, pyridinecarbaldehyde, and thiophenecarbaldehyde gave the corresponding Schiff bases. The products of the condensation of these aminothiazoles with cinnamaldehyde, 1-(2-pyridyl)- and 4-chloro-1-(2,4-difluorophenyl)-5-formyl-3-methyl-6,7-dihydroindazoles, 2-formyl-dimedone, and 2-formyl-1,3-indanedione were also obtained.

2-amino-4-methyl-6-(2-pyridyl)- and 2-amino-4-methyl-6-phenyl-7,8-dihydroindazolo[4,5-d]thiazoles aromatic aldehydes 2-formyl-1,3-cyclanediones Schiff bases 

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© Plenum Publishing Corporation 2004

Authors and Affiliations

  • I. Strakova
  • M. Petrova
  • A. Strakovs

There are no affiliations available

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