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Chemistry of Heterocyclic Compounds

, Volume 40, Issue 7, pp 919–926 | Cite as

Synthesis of 2-Aryl and 2-Hetaryl Derivatives of 2'-Aminospiro[(1,3-dioxane)-5,5'-thiazolin]-4'-one and Spiro[(1,3-dioxane)-5,5'-thiazolidine]2',4'-dione

  • S. M. Ramsh
  • A. G. Ivanenko
  • V. A. Shpilyovy
  • N. L. Medvedskiy
  • P. M. Kushakova
Article

Abstract

2-(Het)aryl derivatives of 2'-aminospiro[(1,3-dioxane)-5,5'-thiazolin]-4'-one or spiro[(1,3-dioxane)-5,5'-thiazolidine]-2',4'-dione are formed by the acid catalyzed interaction of 2-amino-5,5-bis(hydroxymethyl)-4-thiazolinone or its oxo analog 5,5-bis(hydroxymethyl)thiazolidine-2,4-dione with (hetero)aromatic aldehydes.

2-amino-5,5-bis(hydroxymethyl)-4-thiazolinone 2-(het)aryl derivatives of 2'-aminospiro[(1,3-dioxane)-5,5'-thiazolin]-4'-one and spiro[(1,3-dioxane)-5,5'-thiazolidine]-2',4'-dione reactions with aldehydes 

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REFERENCES

  1. 1.
    K. Buler and D. Pearson. Organic Syntheses [Russian translation], Mir, Moscow (1973), 1, p. 582.Google Scholar
  2. 2.
    S. M. Ramsh and A. G. Ivanenko. Khim. Geterotsikl. Soed.,1743 (2003).Google Scholar
  3. 3.
    S. M. Ramsh, N. A. Smorygo, and A. I. Ginak. Khim. Geterotsikl. Soed.,1066 (1984).Google Scholar

Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • S. M. Ramsh
  • A. G. Ivanenko
  • V. A. Shpilyovy
  • N. L. Medvedskiy
  • P. M. Kushakova

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