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Chemistry of Heterocyclic Compounds

, Volume 40, Issue 7, pp 903–910 | Cite as

Ring-Chain Tautomerism of 1,2,3,4-Tetrahydroquinazolines. The Products of Reaction of 1,3-Dicarbonyl Compounds with 2-Aminomethylaniline

  • K. N. Zelenin
  • A. A. Potapov
  • V. V. Alekseyev
  • I. V. Lagoda
Article

Abstract

The reaction of 2-aminomethylaniline with 1,3-dicarbonyl compounds gives a series of 1,2,3,4-tetrahydroquinazoline derivatives. A ring-chain tautomeric equilibrium of the type enamine-1,2,3,4-tetrahydroquinazoline is observed in solutions of these compounds and its position depends of the structure of the starting dicarbonyl component and the solvent polarity.

1,2,3,4-tetrahydroquinazolines ring-chain tautomerism 

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Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • K. N. Zelenin
  • A. A. Potapov
  • V. V. Alekseyev
  • I. V. Lagoda

There are no affiliations available

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