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Reaction of 2-Aminothiazoles and Their Benzo- and Naphtho Derivatives with β-Sulfonyltrifluoromethylvinyldiols

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

By cyclocondensation of 2-aminothiazoles and their benzo and naphtho analogs with β-sulfonyltrifluoromethylvinyldiols, we have obtained a series of novel CF3-containing 6,7-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidines. In the case of the sterically hindered 2-aminothiazoles, heterocyclization does not occur and the corresponding enamino ketones are formed.

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, Moscow, 119899, Russia

    A. L. Krasovsky, A. M. Moiseev, V. G. Nenajdenko & E. S. Balenkova

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  1. A. L. Krasovsky
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  2. A. M. Moiseev
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  3. V. G. Nenajdenko
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  4. E. S. Balenkova
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Krasovsky, A.L., Moiseev, A.M., Nenajdenko, V.G. et al. Reaction of 2-Aminothiazoles and Their Benzo- and Naphtho Derivatives with β-Sulfonyltrifluoromethylvinyldiols. Chemistry of Heterocyclic Compounds 40, 667–675 (2004). https://doi.org/10.1023/B:COHC.0000037324.74693.c6

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  • DOI: https://doi.org/10.1023/B:COHC.0000037324.74693.c6

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