Abstract
Partially hydrogenated thiazolo[3,2-a]pyridines have been synthesized by the interaction of functionally substituted ammonium di- and tetrahydropyridine-2-thiolates with bromocyclohexanone. The structure of 6,8-dicyano-3-hydroxy-5-oxo-1,3-tetramethylene-2,3,4,5,6,7-hexahydrospiro[thiazolo[3,2-a]pyridine-7,1'-(4'-methylcyclohexane)] has been determined by X-ray crystallography.
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REFERENCES
V. P. Litvinov, L. A. Rodinovskaya, Y. A. Sharanin, A. M. Shestopalov, and A. Senning, Sulfur Reports, 13, 1 (1992).
A. Roth and K. Goerlitzer, Arch. Pharm., 326, 642 (1993).
K. Goerlitzer and A. Roth, Pharmazie, 50, 729 (1995).
A. D. Dyachenko, S. M. Desenko, V. D. Dyachenko, and V. P. Litvinov, Khim. Geterotsikl. Soed.,554 (2000).
A Krauze and G. Duburs, Khim. Geterotsikl. Soed.,1134 (1996).
A. M. Shestopalov, L. A. Rodinovskaya, Yu. A. Sharanin, and V. I. Litvinov, Zhur. Org. Khim., 58, 840 (1988).
V. I. Litvinov, A. M. Shestopalov, Yu. A Sharanin, V. Yu. Mortikov, and V. N. Nesterov, Doklad. Akad. Nauk., 299, 135 (1988).
N. S. Zefirov and V. A. Palyuyulin, Doklad. Akad. Nauk, 252,111 (1980).
M. Burke-Laing and M. Laing, Acta Crystallogr., B32, 3216 (1976).
F. H. Allen, O. Kennard, D. G. Watson, L. Brammer, A. G. Orpen, and R. Taylor, J. Chem. Soc., Perkin Trans. 2, P S1 (1987).
A. C. T. North, D. C. Phillips, F. Scott, and F. S. Mathews, Acta Crystallogr., A24, 351 (1968).
D. J. Watkin, C. K. Prout, J. R. Carruthers, and P. W. Betteridge, CRYSTALS Issue 10,Chemical Crstallograhy Laboratory, Univ. of Oxford (1966).
J. R. Carruthers and D. J. Watkin, Acta Crystallogr., A35, 698 (1979).
V. D. Dyachenko, Diss. Doctor Khim. Nauk, Moscow (1998).
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Dyachenko, A.D., Desenko, S.M., Dyachenko, V.D. et al. A New Route to Partially Hydrogenated Thiazolo[3,2-a]pyridine. Chemistry of Heterocyclic Compounds 40, 650–659 (2004). https://doi.org/10.1023/B:COHC.0000037322.78539.cc
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DOI: https://doi.org/10.1023/B:COHC.0000037322.78539.cc