Skip to main content
Log in

Synthesis of N-Substituted -Alkoxy-3-aryl-4-methyl-2,5-dihydro-2-pyrrolones

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

5-Alkoxy-1-aralkyl-3-aryl-4-methyl-2,5-dihydro-2-pyrrolones and the corresponding alkylthio derivatives were synthesized for the first time through the intermediate formation of unsymmetrical maleimides. The possibility of wide variation of the substituents at positions 1, 3, and 5 of the 2-pyrrolones was demonstrated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. K. Moriyasu, H. Akieda, H. Aoki, M. Suzuki, S. Matsuto, Y. Iwasaki, S. Koda, and K. Tomiya, US Patent 5409886; Chem. Abstr., 124, P8680 (1995).

    Google Scholar 

  2. N. Ohba, A. Ikeda, K. Matsunari, Y. Yamada, M. Hirata, Y. Nakamura, A. Takeuchi, and H. Karino, US Patent 5006157; Chem. Abstr., 114, 247145 (1991).

    Google Scholar 

  3. B. Boehner and M. Baumann, Swiss. Pat. 633678; Chem. Abstr., 98, 121386 (1983).

    Google Scholar 

  4. B. Boehner and M. Baumann, German Patent 2735841; Chem. Abstr., 88, 152415 (1978).

    Google Scholar 

  5. T. Kume, T. Goto, M. Honmachida, A. K. Amochi, A. Yanagi, S. Yagi, and S. Miyachi, European Patent 0286816 (1988); Chem. Abstr., 110, 135246 (1989).

    Google Scholar 

  6. H. Kinoshita, Y. Hayashi, Y. Murata, and K. Inomata, Chem. Lett., 1437 (1993).

  7. C. S. Rondestvedt and O. Vogl, J. Am. Chem. Soc., 77, 2313 (1955).

    Google Scholar 

  8. M. S. Newman and W. M. Stallick, J. Org. Chem., 38, 3386 (1973).

    Google Scholar 

  9. W. D. Dean and D. M. Blum, J. Org. Chem., 58, 7916 (1993).

    Google Scholar 

  10. E. K. Fields, S. J. Behrend, S. Meyerson, M. L. Winzenburg, B. R. Ortega, and H. K. Hall, J. Org. Chem., 55, 5165 (1990).

    Google Scholar 

  11. G. B. Gill, G. D. James, K. V. Gates, and G. Pattenden, J. Chem. Soc. Perkin Trans. 1, 2567 (1993).

    Google Scholar 

  12. F. Farina, M. V. Martin, and M. C. Paredes, Heterocycles, 22, 1733 (1984).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nikitin, K.V., Andryukhova, N.P. Synthesis of N-Substituted -Alkoxy-3-aryl-4-methyl-2,5-dihydro-2-pyrrolones. Chemistry of Heterocyclic Compounds 40, 561–569 (2004). https://doi.org/10.1023/B:COHC.0000037310.26204.24

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:COHC.0000037310.26204.24

Navigation