Skip to main content
SpringerLink
Log in

The Kost-Sagitullin Rearrangement in a Series of 1-Alkyl-2-(carbamoylmethyl)-4,6-dimethylpyrimidinium Iodides

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The rearrangement of 1-alkyl-2-(carbamoylmethyl)pyrimidinium iodides into substituted 2-alkylaminonicotinamides occurring in alcoholic solutions of amines has been studied. It was shown that in the presence of water the rearrangement of 2-(carbamoylmethyl)-1,4,6-trimethylpyrimidinium iodide is accompanied by the formation of a derivative of 2-oxo-1,2-dihydronicotinic acid, and under the action of ethylamine a “rearrangement and transamination” occurs leading to 2-ethylamino-4,6-dimethylnicotinamide.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. G. G. Danagulyan, L. G. Sahakyan, and G. A. Panosyan, Khim. Zh. Armen., 53, 62 (2000).

    Google Scholar 

  2. G. G. Danagulyan, L. G. Sahakyan, A. R. Katritzky, and S. N. Denisenko, Heterocycles, 53, 419 (2000).

    Google Scholar 

  3. G. G. Danagulyan and L. G. Sahakyan, Khim. Geterotsikl. Soedin., 698 (2000).

  4. G. G. Danagulyan, L. G. Sahakyan, and G. A. Panosyan, Khim. Geterotsikl. Soedin., 351 (2001).

  5. G. G. Danagulyan and L. G. Sahakyan, Khim. Geterotsikl. Soedin., 1434 (1999).

  6. G. G. Danagulyan and L. G. Sahakyan, Khim. Zh. Armen., 53, 147 (2000).

    Google Scholar 

  7. G. G. Danagulyan, L. G. Sahakyan, A. R. Katritzky, and S. N. Denisenko, Khim. Geterotsikl. Soedin., 1572 (1999).

Download references

Author information

Authors and Affiliations

  1. Institute of Organic Chemistry, National Academy of Sciences of the Armenian Republic, Erevan, 375094

    G. G. Danagulyan & L. G. Sahakyan

Authors
  1. G. G. Danagulyan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. G. Sahakyan
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Danagulyan, G.G., Sahakyan, L.G. The Kost-Sagitullin Rearrangement in a Series of 1-Alkyl-2-(carbamoylmethyl)-4,6-dimethylpyrimidinium Iodides. Chemistry of Heterocyclic Compounds 40, 320–325 (2004). https://doi.org/10.1023/B:COHC.0000028628.69948.b6

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:COHC.0000028628.69948.b6

Search

Navigation