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Chemistry of Heterocyclic Compounds

, Volume 40, Issue 2, pp 154–160 | Cite as

Isomerization of (Het)arylbenzoins in Basic Media

  • S. P. Ivonin
  • A. V. Lapandin
  • V. G. Shtamburg
Article

Abstract

The α→β isomerization of the hetaryl analogs of unsymmetrical benzoins on heating in basic media is a convenient preparative method for the production of α-hydroxyacyl derivatives of π-excessive heterocycles. The motivating force here for the isomerization is the formation of a thermodynamically more stable product. It was established that α→β isomerization is promoted by increase in the difference between the electron-donating characteristics of the (het)aryl residues

benzoins π-excessive heterocycles isomerization 

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Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • S. P. Ivonin
    • 1
  • A. V. Lapandin
    • 1
  • V. G. Shtamburg
    • 1
  1. 1.Dnepropetrovsk National UniversityDnepropetrovskUkraine

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