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Steric Effects in the Nucleophilic Addition of Pyrazoles Unsubstituted at a Nitrogen Atom to the Double Bond of Maleic Anhydride

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Only one isomer, 5-methyl-3-phenyl-1-pyrazolylsuccinic acid, is formed on addition of 3(5)-methyl-5(3)-phenylpyrazole to the double bond of maleic anhydride.

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Nam, N.L., Grandberg, I.I. & Sorokin, V.I. Steric Effects in the Nucleophilic Addition of Pyrazoles Unsubstituted at a Nitrogen Atom to the Double Bond of Maleic Anhydride. Chemistry of Heterocyclic Compounds 39, 1314–1316 (2003). https://doi.org/10.1023/B:COHC.0000010645.76851.0f

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  • DOI: https://doi.org/10.1023/B:COHC.0000010645.76851.0f

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