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Cyclocondensation of 2-Aminobenzimidazole with Dimedone and Its Arylidene Derivatives

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Abstract

The reactions of 2-aminobenzimidazole with substituted benzaldehydes and dimedone, 2-arylidene derivatives of dimedone, 9-arylhexahydro-1H-xanthene-1,8(2H)-diones and also with dimedone and DMF have been studied. The direction of formation of the pyrimidine ring has been established and discussed. An X-ray structural investigation of 2,2-dimethyl-2,3-dihydrobenzimidazo[1,2-a]quinazolin-4(1H)-one has been carried out.

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Authors and Affiliations

  1. Ukraine Academy of Medical Sciences, V. Ya. Danilevsky Institute for Problems in Endocrine Pathology, Kharkov, 61002

    V. V. Lipson & M. G. Shirobokova

  2. V. N. Karazin National University, Kharkov, 61077, Ukraine

    S. M. Desenko & V. D. Orlov

  3. Institute of Single Crystals, Kharkov, 61001, Ukraine

    S. M. Desenko, S. V. Shishkina & O. V. Shishkin

Authors
  1. V. V. Lipson
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  2. S. M. Desenko
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  3. S. V. Shishkina
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  4. M. G. Shirobokova
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  5. O. V. Shishkin
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  6. V. D. Orlov
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Lipson, V.V., Desenko, S.M., Shishkina, S.V. et al. Cyclocondensation of 2-Aminobenzimidazole with Dimedone and Its Arylidene Derivatives. Chemistry of Heterocyclic Compounds 39, 1041–1047 (2003). https://doi.org/10.1023/B:COHC.0000003522.71893.77

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  • DOI: https://doi.org/10.1023/B:COHC.0000003522.71893.77

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