Abstract
A synthesis is reported for α-bromo-4-difluoromethylthioacetophenone and the conditions for the condensation of this compound with 2-aminothiazole, 2-amino-5-chloropyridine, 2-amino-4,5-dihydro-3H-pyrrole, benzimidazoline-2-thione, oxadiazoline-2-thione, and thiourea were studied. S- and N-substituted azaheterocycles containing the 4-(difluoromethylthio)phenyl fragment were synthesized and characterized.
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Demchenko, A.M., Nazarenko, K.G., Andrushko, A.P. et al. Synthesis and Reactivity of α-Bromo-4-(difluoromethylthio)acetophenone. Chemistry of Heterocyclic Compounds 39, 965–969 (2003). https://doi.org/10.1023/A:1026114908997
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DOI: https://doi.org/10.1023/A:1026114908997