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Synthesis of 4-Amino-6-R-4,5-dihydro-3-phenacylthio-1,2,4-triazin-5-ones and 8H-3-R-7-Aryl-1,2,4-triazino[3,4-b][1,3,4]thiadiazin-4-ones

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Abstract

A study was carried out on the reaction of 4-amino-6-R-2,3,4,5-tetrahydro-3-thioxo-1,2,4-triazin-5-ones with halo ketones in alkaline media to yield 4-amino-6-R-4,5-dihydro-3-phenacylthio-1,2,4-triazin-5-ones, which then convert to 8H-3-R-7-aryl-1,2,4-triazino[3,4-b][1,3,4]thiadiazin-4-ones.

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Authors and Affiliations

  1. Ukraine National Academy of Sciences, Institute of Organic Chemistry, Kiev, 02094

    I. M. Bazavova, V. N. Britsun, A. N. Esipenko & M. O. Lozinskii

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  1. I. M. Bazavova
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  2. V. N. Britsun
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  3. A. N. Esipenko
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  4. M. O. Lozinskii
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Bazavova, I.M., Britsun, V.N., Esipenko, A.N. et al. Synthesis of 4-Amino-6-R-4,5-dihydro-3-phenacylthio-1,2,4-triazin-5-ones and 8H-3-R-7-Aryl-1,2,4-triazino[3,4-b][1,3,4]thiadiazin-4-ones. Chemistry of Heterocyclic Compounds 39, 809–812 (2003). https://doi.org/10.1023/A:1025615700509

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  • DOI: https://doi.org/10.1023/A:1025615700509

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